Metpio

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Metpio Information

Metpio is a prescription medicine that is available as a Tablet. Other than this, Metpio has some other therapeutic uses, which have been discussed ahead.

The right dosage of Metpio depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.

Common side effects of Metpio include Stomach Upset, Difficulty urinating, Muscle Ache. While these are the most often observed Metpio side effects, there are can be others also. These have been listed below. Usually, these side effects of Metpio go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

Metpio's effect during pregnancy is Moderate and Moderate while nursing. Warnings related to Metpio's effects on the liver, heart and kidney, if any, have been listed below.

Metpio is not recommended if you suffer from certain medical conditions as it can have adverse effects. Congestive Heart Failure (CHF), Anemia, Shock are examples of such conditions. Some other conditions that can be affected by Metpio are listed in the contraindications section below.

Drug interactions for Metpio have been reported in the medical literature. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Metpio is considered safe while driving, and is addictive.



Metpio Benefits & Uses

Metpio is used to treat the following -

Other Benefits

  • Diabetes Type 2

Metpio Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 515 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 15 mg pioglitazone and 500 mg metformin
Geriatric
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 865 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 15 mg pioglitazone and 850 mg metformin

Metpio Related Warnings

  • Is the use of Metpio safe for pregnant women?


    Metpio may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Metpio again without your doctor's advice.

  • Is the use of Metpio safe during breastfeeding?


    Women who are breastfeeding can experience some moderate side effects of Metpio. Immediately discontinue Metpio if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

  • What is the effect of Metpio on the Kidneys?


    Metpio rarely harms the kidneys.

  • What is the effect of Metpio on the Liver?


    Metpio may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

  • What is the effect of Metpio on the Heart?


    You may experience side effects on your heart after taking Metpio. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.



Severe Interaction of Metpio with Other Drugs

Metpio should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Metpio Contraindications

If you are suffering from any of the following diseases, you should not take Metpio unless your doctor advises you to do so -



Frequently asked Questions about Metpio

  • Is this Metpio habit forming or addictive?


    No, you will not get addicted to Metpio.

Metpio Interactions with Food and Alcohol

  • Interaction between Food and Metpio


    Information is not available on the interaction of any foods with Metpio, due to a lack of research on this.

  • Interaction between Alcohol and Metpio


    Taking [medicine] and alcohol at the same time may lead to mild side effects. Contact your doctor right away if you observe any side effects.



Frequently asked Questions about Metpio

Question about 5 years ago

Is Metpio safe to use?

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, Metpio is safe to use, many people have side effects at first, they usually diminish and then go away completely in a few weeks. A few people find they cannot tolerate metformin, there are other drugs but metformin is usually the first choice. It is very safe

Question over 4 years ago

How does Metpio increase lactic acidosis?

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Metpio treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Metpio induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Question almost 5 years ago

Does Metpio cause sleep problems?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Yes, Metpio can cause some sleep problems, especially insomnia. On the other hand, Metpio has proven to be useful for preventing sleep apnea. The exact relationship between Metpio and sleep problems is still not clear, and further studies are needed for a clearer understanding.

Question about 5 years ago

What are the uses of Metpio?

Dr. Haleema Yezdani MBBS , General Physician

Metpio is used with a proper diet and exercise program, to treat diabetes. It is also used with other medication to reduce the high blood sugar. It is used in a patient with type2 diabetes. It is also used in the treatment of polycystic ovarian syndrome (PCOS) and cancer.

Question over 5 years ago

What is Metpio?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Metpio contain metformin, is an oral antidiabetic drug which belongs to the class of biguanide. It is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. Moreover, it also reduces the risk of cardiovascular complications of diabetes.



See all substitutes for Metpio


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Actos (pioglitazone hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 276-277

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1032-1033

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