Pyrazinamide + Isoniazid + Rifampicin Benefits & Uses

Pyrazinamide + Isoniazid + Rifampicin is used to treat the following -

Other Benefits

Tuberculosis

Pyrazinamide + Isoniazid + Rifampicin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group

Dosage

Pyrazinamide + Isoniazid + Rifampicin Side Effects

Based on research, the following side effects have been observed when Pyrazinamide + Isoniazid + Rifampicin is used -

Moderate

Increased Liver Enzymes

Common

Rash
Erythema
Discoloration of Urine
Urticaria
Nausea or vomiting
Diarrhoea
Stomach ache (Read More - Home remedies for stomach pain)
Joint pain
Bone Pain

Pyrazinamide + Isoniazid + Rifampicin Related Warnings

Is the use of Pyrazinamide + Isoniazid + Rifampicin safe for pregnant women?

Pyrazinamide + Isoniazid + Rifampicin may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Pyrazinamide + Isoniazid + Rifampicin again without your doctor's advice.

Moderate
Is the use of Pyrazinamide + Isoniazid + Rifampicin safe during breastfeeding?

Women who are breastfeeding can experience some moderate side effects of Pyrazinamide + Isoniazid + Rifampicin. Immediately discontinue Pyrazinamide + Isoniazid + Rifampicin if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

Moderate
What is the effect of Pyrazinamide + Isoniazid + Rifampicin on the Kidneys?

There can be some harmful effects on your kidneys after taking Pyrazinamide + Isoniazid + Rifampicin. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

Moderate
What is the effect of Pyrazinamide + Isoniazid + Rifampicin on the Liver?

There may be an adverse effect on the liver after taking Pyrazinamide + Isoniazid + Rifampicin. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

Moderate
What is the effect of Pyrazinamide + Isoniazid + Rifampicin on the Heart?

Pyrazinamide + Isoniazid + Rifampicin may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

Moderate

Severe Interaction of Pyrazinamide + Isoniazid + Rifampicin with Other Drugs

Pyrazinamide + Isoniazid + Rifampicin should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Pyrazinamide + Isoniazid + Rifampicin Contraindications

If you are suffering from any of the following diseases, you should not take Pyrazinamide + Isoniazid + Rifampicin unless your doctor advises you to do so -

Liver Cirrhosis
Liver Disease
Kidney Disease
Heart Disease

Frequently asked Questions about Pyrazinamide + Isoniazid + Rifampicin

Is this Pyrazinamide + Isoniazid + Rifampicin habit forming or addictive?

Pyrazinamide + Isoniazid + Rifampicin does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking Pyrazinamide + Isoniazid + Rifampicin as you may feel sleepy.

Dangerous
Is it safe?

Yes, but take Pyrazinamide + Isoniazid + Rifampicin only as per medical advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Pyrazinamide + Isoniazid + Rifampicin is not used to treat mental disorders.

No

Pyrazinamide + Isoniazid + Rifampicin Interactions with Food and Alcohol

Interaction between Food and Pyrazinamide + Isoniazid + Rifampicin

Taking Pyrazinamide + Isoniazid + Rifampicin with food does not cause any problems.

Safe
Interaction between Alcohol and Pyrazinamide + Isoniazid + Rifampicin

Taking alcohol with Pyrazinamide + Isoniazid + Rifampicin can be dangerous.

Severe

See all substitutes for Pyrazinamide + Isoniazid + Rifampicin

Pyrazinamide + Isoniazid + Rifampicin Kit - ₹22

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 768-769

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1066-1067

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Isoniazid

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 765-767

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 715-716

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Rifadin (rifampin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 767-768

Product Description [Internet]: RIFATER® (rifampin, isoniazid and pyrazinamide USP). USFDA

Product Description [Internet]: RIFADIN®. USFDA

Product Description [Internet]: ISONIAZID. Alliance Pharmaceuticals Limited

Pyrazinamide + Isoniazid + Rifampicin

Medicines based on Pyrazinamide Isoniazid Rifampicin

Pyrazinamide + Isoniazid + Rifampicin Information