Silymarin



  • Manufactured by:
  • Contains / Salt: Silymarin


Silymarin Information

Silymarin is a prescription medicine. It is typically used for the treatment of Cholestatic Liver Diseases. The alternative uses of Silymarin have also been explained below.

The correct dosage of Silymarin depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.

Common side effects of Silymarin include Indigestion, Bloating or fullness, Diarrhoea. Usually, these side effects of Silymarin go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Silymarin is Moderate for pregnant women and Unknown for women who are breastfeeding. It is important to know if Silymarin has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Silymarin related warnings section.

Other conditions have been mentioned below in the Silymarin contraindications section.

Drug reaction of Silymarin with other medicines has been reported. See below for a complete list.

In addition to the above precautions for Silymarin, it is important to know that it is safe while driving, and is habit-forming.



Silymarin Benefits & Uses

Silymarin is used to treat the following -

Other Benefits

  • Non-Alcoholic Fatty Liver Disease
  • Alcoholic Fatty Liver Disease

Silymarin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Cholestatic Liver Diseases
  • Before or After Meal: With meal
  • Single Maximum Dose: 140 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
Geriatric
  • Disease: Cholestatic Liver Diseases
  • Before or After Meal: With meal
  • Single Maximum Dose: 140 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
13 - 18 years (Adolescent)
  • Disease: Cholestatic Liver Diseases
  • Before or After Meal: With meal
  • Single Maximum Dose: 70 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice, dose may increase according to body weight

Silymarin Related Warnings

  • Is the use of Silymarin safe for pregnant women?


    Silymarin may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Silymarin again without your doctor's advice.

    Moderate
  • Is the use of Silymarin safe during breastfeeding?


    Information about safety of Silymarin for women who are breastfeeding is not available since scientific research on this is yet to be done.

    Unknown
  • What is the effect of Silymarin on the Kidneys?


    Silymarin has very mild side effects on the kidneys.

    Mild
  • What is the effect of Silymarin on the Liver?


    Silymarin may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Silymarin on the Heart?


    Side effects of Silymarin rarely affect the heart.

    Mild


Severe Interaction of Silymarin with Other Drugs

Silymarin should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Silymarin Contraindications

If you are suffering from any of the following diseases, you should not take Silymarin unless your doctor advises you to do so -



Frequently asked Questions about Silymarin

  • Is this Silymarin habit forming or addictive?


    Forming a habit of Silymarin has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Silymarin since it will not make you feel sleepy.

    Safe
  • Is it safe?


    There are no side effects of Silymarin, so it is safe for use.

    Safe
  • Is it able to treat mental disorders?


    No, Silymarin is not used to treat mental disorders.

    No

Silymarin Interactions with Food and Alcohol

  • Interaction between Food and Silymarin


    Information is not available on the interaction of any foods with Silymarin, due to a lack of research on this.

    Unknown
  • Interaction between Alcohol and Silymarin


    Information about the interaction of Silymarin and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Silymarin

Question over 4 years ago

Can Silymarin treat hepatitis B?

Aakash Shah MBBS, MBBS , General Physician

No, Silymarin does not treat hepatitis B because it is not an antiviral drug. However, it is used in combination with other drugs in the treatment of hepatitis.

Question almost 5 years ago

Is Silymarin safe to use?

Dr. Faisal Mukhtar MBBS, PG Dip, DNB , Ophthalmology

Yes, Silymarin is safe to use, if taken in a prescribed amount for a specified time as advised by the doctor. However, some side effects have been observed at regular doses these are bloating, flatulence, and loss of appetite. Do not hesitate to inform your doctor if you are facing any of the above.

Question about 5 years ago

What is Silymarin?

Dr. Chinmaya Bal MBBS , General Physician

Silymarin is a brand name of silymarin and it comes in form of tablet, capsule, and suspension. It is a prescription drug that belongs to the class of drug known as polyphenolic flavonoid that possesses antioxidant, anti-inflammatory, anticancer, and cardioprotective properties. It is used for the treatment of liver diseases.

Question over 4 years ago

Can Silymarin cure fatty liver?

Dr. Amit Singh MBBS , General Physician

Silymarin is used in the treatment of fatty liver in combination with other drugs. It helps in improving liver functions with assists in speedy recovery.

Question almost 5 years ago

Does Silymarin lower cholesterol?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Yes, Silymarin lowers cholesterol levels in the blood because it inhibits the synthesis of bad cholesterol (LDL and VLDL) and it also increases the levels of good cholesterol (HDL) in our body. 



See all substitutes for Silymarin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1344-1345

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