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Chloramphenicol + Polymyxin B is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Adult |
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Geriatric |
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Is the use of Chloramphenicol + Polymyxin B safe for pregnant women?
The effects of Chloramphenicol + Polymyxin B on pregnant women are unknown since no research has been done to ascertain it yet.
Is the use of Chloramphenicol + Polymyxin B safe during breastfeeding?
Due to lack of research work on this topic, the side effects of Chloramphenicol + Polymyxin B for breastfeeding women are not known.
What is the effect of Chloramphenicol + Polymyxin B on the Kidneys?
Very few cases of side effects of Chloramphenicol + Polymyxin B on kidney have been reported.
What is the effect of Chloramphenicol + Polymyxin B on the Liver?
Using Chloramphenicol + Polymyxin B does not have any harmful effects on the liver.
What is the effect of Chloramphenicol + Polymyxin B on the Heart?
You can take Chloramphenicol + Polymyxin B without any fear of damage to the heart.
Chloramphenicol + Polymyxin B should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Chloramphenicol + Polymyxin B unless your doctor advises you to do so -
Is this Chloramphenicol + Polymyxin B habit forming or addictive?
No, there is no any evidence that Chloramphenicol + Polymyxin B is addictive.
Interaction between Food and Chloramphenicol + Polymyxin B
Taking Chloramphenicol + Polymyxin B with food does not cause any problems.
Interaction between Alcohol and Chloramphenicol + Polymyxin B
Due to lack of research, there is no information about the side effects of taking Chloramphenicol + Polymyxin B with alcohol.
Yes, Chloramphenicol + Polymyxin B is helpful in typhoid fever. It is used in the management of acute typhoid fever caused by Salmonella species. It is usually given after 8 -10 days of the treatment when the fever of the patient is completely going down over this duration to prevent the relapse of the typhoid infection.
No, Chloramphenicol + Polymyxin B does not cause weight loss. It has not been reported by the patients who are taking this drug. However, some of the animal studies have reported weight loss after long-term use of this drug. If you are experiencing unusual weight loss and you are in doubt that Chloramphenicol + Polymyxin B is causing weight loss then discuss with your doctor instantly.
Chloramphenicol + Polymyxin B is bacteriostatic at the therapeutic dose that means it inhibits the growth of the bacteria but it can be bactericidal at higher doses. It works by inhibiting the protein synthesis in bacteria which it needs to survive. In the absence of protein synthesis, the bacterial growth is stunned and slowed.
Yes, Chloramphenicol + Polymyxin B is an antibiotic. It contains chloramphenicol which is a broad spectrum antibiotic that belongs to the class of drugs known as amphenicols. It is used for the prevention and treatment of various bacterial infections. It is mainly used in the treatment of parrot fever, rickettsial infection, cystic fibrosis, pneumonia, and also sometimes in the management of typhoid fever.
Chloramphenicol + Polymyxin B contains chloramphenicol which is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the protein synthesis in bacteria which needs to survive. In the absence of protein, the bacterial growth is stunned and slowed. It can also kill the bacteria in higher doses. Chloramphenicol + Polymyxin B is effective against a wide range of both gram negative and gram positive bacteria such as Salmonella species, Rickettsia species, Neisseria meningitidis, Escherichia coli, Haemophilus influenzae, and Staphylococcus pneumoniae.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Polymyxin B
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 759