Combinam

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  • Contains / Salt: Ibuprofen (400 mg) + Paracetamol (325 mg)
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Combinam Information

Combinam is a commercial drug that is prescribed in the form of Tablet. Secondary and off-label uses of Combinam have also been mentioned below.

Medical history of the patient along with age and gender determines the dosage of Combinam. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

The most common side effects of Combinam are Nausea or vomiting, Diarrhoea, Constipation. Besides the aforementioned side effects, there are other adverse effects of Combinam as well, which are listed below. These side effects of Combinam are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Combinam is Moderate for pregnant women and Moderate for women who are breastfeeding. Further, the section on Combinam related warnings talks about Combinam's effects on the liver, heart and kidney.

Individuals suffering from medical conditions like Allergy, Gastrointestinal Bleeding, Kidney Disease must refrain from the use of Combinam since this can cause severe adverse effects. Other contraindications of Combinam have been discussed in the sections ahead.

Additionally, Combinam may also adversely react with other medicines. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Combinam is considered safe while driving, and is addictive.



Combinam Benefits & Uses

Combinam is used to treat the following -

Other Benefits

Combinam Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Ibuprofen (400 mg)/ Paracetamol (325 mg)
Adult
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Ibuprofen (400 mg)/ Paracetamol (325 mg)
Geriatric
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Ibuprofen (400 mg)/ Paracetamol (325 mg)

Combinam Related Warnings

  • Is the use of Combinam safe for pregnant women?


    Combinam can have harmful effects in pregnant women. If you experience any discomfort after using Combinam, then discontinue the use and take your doctor's advice.

    Moderate
  • Is the use of Combinam safe during breastfeeding?


    Women who are breastfeeding can experience some moderate side effects of Combinam. Immediately discontinue Combinam if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

    Moderate
  • What is the effect of Combinam on the Kidneys?


    Combinam has very mild side effects on the kidneys.

    Mild
  • What is the effect of Combinam on the Liver?


    Side effects of Combinam rarely affect the liver.

    Mild
  • What is the effect of Combinam on the Heart?


    Combinam may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Combinam with Other Drugs

Combinam should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Combinam Contraindications

If you are suffering from any of the following diseases, you should not take Combinam unless your doctor advises you to do so -



Frequently asked Questions about Combinam

  • Is this Combinam habit forming or addictive?


    No, you will not get addicted to Combinam.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Combinam since it does not cause drowsiness.

    Safe
  • Is it safe?


    Yes, but consume Combinam only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Combinam in mental disorders is not effective.

    No

Combinam Interactions with Food and Alcohol

  • Interaction between Food and Combinam


    It is safe to take Combinam with food.

    Safe
  • Interaction between Alcohol and Combinam


    Information about the interaction of Combinam and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Combinam

Question about 5 years ago

Can Combinam cause kidney damage?

Dr. Kapil Sharma MBBS , General Physician

Painkillers like Combinam should not be used if there is decreased kidney function as they may reduce the supply of blood to the kidneys. Also, long-term use can also impair the normal kidneys. Therefore, it is important that you talk to your doctor in case you have reduced kidney function. You should use Combinam exactly as prescribed by your doctor. 

Question over 4 years ago

Is Combinam safe in migraine?

Dr. Yogesh Kumar MBBS , General Physician

Yes, Combinam is suitable for the treatment of a migraine as it leads to pain alleviation. Several studies have also documented the efficacy of Combinam in migraine pain. However, if you don't get a relief from Combinam, please talk to your doctor immediately to prescribe your other options. 

Question over 5 years ago

What is Combinam?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Combinam is a non-steroidal anti-inflammatory drug (NSAID) which is used for the treatment of tenderness, swelling, stiffness, and pain associated with osteoarthritis in which there is a breakdown of the lining of the joints, and rheumatoid arthritis in which there is swelling of the lining of the joints. It is also used for alleviation of the menstrual pain, before and during the menstrual cycle. It is also used to relieve fever and pain associated with a headache, minor aches, sprains, common cold, toothache, and backache. It also shows the antiplatelet effect which means it prevents the formation of blood clots. Combinam is used for the treatment of psoriatic arthritis (a chronic skin disease causing scaling and swelling), gouty arthritis (which develops from the built up of some chemical in the joints) and ankylosing spondylitis (arthritis that affects the spine).

Question about 5 years ago

For how long can I take Combinam?

Dr. Saikat Mukherjee MBBS , General Physician

Combinam should be taken as long as it has been prescribed by your doctor. Longterm use is associated with various adverse effects like stomach upset, kidney damage, heart problems, etc., therefore, stop the usage if you experience any adverse effect.

Question over 4 years ago

How safe is Combinam for children?

Dr. Yogesh Kumar MBBS , General Physician

Yes, Combinam is safe to be used in children. It is the only drug which is approved to be used in children over 3 months of age. It has a good tolerability profile in children because of which it is used for the management of inflammation, mild pains, and fever in them. The pediatrician will direct you the correct dose and way to give it to your child.



See all substitutes for Combinam


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 666-668

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 200

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Motrin® (Ibuprofen)

KD Tripathi. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 206-207

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Acetaminophen (acetaminophen)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ofirmev (acetaminophen)

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