Dacarbazine



  • Manufactured by:
  • Contains / Salt: Dacarbazine


Dacarbazine Information



Dacarbazine Benefits & Uses

Dacarbazine is used to treat the following -

Main Benefits

  • Metastatic Melanoma

Other Benefits

Dacarbazine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Skin Cancer (Melanoma)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 4.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 10 days
  • Special Instructions: Repeat every 4 Weeks
Geriatric
  • Disease: Skin Cancer (Melanoma)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 4.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 10 days
  • Special Instructions: Repeat every 4 Weeks
13 - 18 years (Adolescent)
  • Disease: Hodgkin Lymphoma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 250 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 5 days
  • Special Instructions: Repeat every 4 Weeks
2 - 12 years (Child)
  • Disease: Hodgkin Lymphoma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 250 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 5 days
  • Special Instructions: Repeat every 4 Weeks


Dacarbazine Side Effects

Based on research, the following side effects have been observed when Dacarbazine is used -

Moderate

  • Erythema
  • Increased Liver Enzymes

Mild

Dacarbazine Related Warnings

  • Is the use of Dacarbazine safe for pregnant women?


    Pregnant women may get severe side effects after taking Dacarbazine. If you are pregnant, do not take Dacarbazine without a doctor's advice.

    Severe
  • Is the use of Dacarbazine safe during breastfeeding?


    Dacarbazine may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Dacarbazine, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Dacarbazine.

    Moderate
  • What is the effect of Dacarbazine on the Kidneys?


    Dacarbazine has very mild side effects on the kidneys.

    Mild
  • What is the effect of Dacarbazine on the Liver?


    Dacarbazine is rarely harmful for the liver.

    Mild
  • What is the effect of Dacarbazine on the Heart?


    Very few cases of side effects of Dacarbazine on the heart have been reported.

    Mild


Severe Interaction of Dacarbazine with Other Drugs

Dacarbazine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Dacarbazine Contraindications

If you are suffering from any of the following diseases, you should not take Dacarbazine unless your doctor advises you to do so -



Frequently asked Questions about Dacarbazine

  • Is this Dacarbazine habit forming or addictive?


    Dacarbazine does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Dacarbazine you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, Dacarbazine is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Dacarbazine for mental disorders.

    No

Dacarbazine Interactions with Food and Alcohol

  • Interaction between Food and Dacarbazine


    Taking Dacarbazine with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Dacarbazine


    Information about the interaction of Dacarbazine and alcohol is not currently available because this topic has not been researched yet.

    Unknown


See all substitutes for Dacarbazine


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 388-389

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 861

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Dbl™ dacarbazine (dacarbazine)



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