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Metformin + Repaglinide is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Based on research, the following side effects have been observed when Metformin + Repaglinide is used -
Severe
Moderate
Mild
Common
Is the use of Metformin + Repaglinide safe for pregnant women?
Metformin + Repaglinide shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.
Is the use of Metformin + Repaglinide safe during breastfeeding?
Metformin + Repaglinide may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.
What is the effect of Metformin + Repaglinide on the Kidneys?
There may be some adverse effects on kidney after taking Metformin + Repaglinide. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.
What is the effect of Metformin + Repaglinide on the Liver?
Metformin + Repaglinide may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
What is the effect of Metformin + Repaglinide on the Heart?
Metformin + Repaglinide has very mild side effects on the heart.
Metformin + Repaglinide should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Metformin + Repaglinide unless your doctor advises you to do so -
Is this Metformin + Repaglinide habit forming or addictive?
No, there is no any evidence that Metformin + Repaglinide is addictive.
Interaction between Food and Metformin + Repaglinide
There is no information on the effects of taking Metformin + Repaglinide with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Metformin + Repaglinide
Consumption of alcohol and Metformin + Repaglinide together may have severe effects on your health.
Metformin + Repaglinide increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.
Lactic acidosis associated with Metformin + Repaglinide treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Metformin + Repaglinide induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.
Yes, Metformin + Repaglinide can cause some sleep problems, especially insomnia. On the other hand, Metformin + Repaglinide has proven to be useful for preventing sleep apnea. The exact relationship between Metformin + Repaglinide and sleep problems is still not clear, and further studies are needed for a clearer understanding.
Metformin + Repaglinide is used with a proper diet and exercise program, to treat diabetes. It is also used with other medication to reduce the high blood sugar. It is used in a patient with type2 diabetes. It is also used in the treatment of polycystic ovarian syndrome (PCOS) and cancer.
Yes, you can take Metformin + Repaglinide with a beta-blocker. People with diabetes tend to develop heart disease or stroke at an earlier age than the general population. One reason for this is that high glucose levels increase your risk of high blood pressure (hypertension). No harmful interactions are seen between them. However, a recent study suggests that beta-blockers can decrease the plasma level of Metformin + Repaglinide and long-term use can increase lactic acid and uric acid in the blood.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prandin® (repaglinide)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 273