Topotecan

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Topotecan Information



Topotecan Benefits & Uses

Topotecan is used to treat the following -

Other Benefits

Topotecan Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult(Female)
  • Disease: Ovarian Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2.5 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 3 weeks
  • Special Instructions: Given for 5 consecutive days, starting on day 1 of a 21 day course, 1.5 mg/ m(2)
Adult
  • Disease: Small Cell Lung Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2.5 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 3 weeks
  • Special Instructions: Given for 5 consecutive days, starting on day 1 of a 21 day course, 1.5 mg/ m(2)
Geriatric
  • Disease: Small Cell Lung Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2.5 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 3 weeks
  • Special Instructions: Given for 5 consecutive days, starting on day 1 of a 21 day course, 1.5 mg/ m(2)

Topotecan Related Warnings

  • Is the use of Topotecan safe for pregnant women?


    Topotecan can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Topotecan safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Topotecan. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Topotecan on the Kidneys?


    Very few cases of side effects of Topotecan on kidney have been reported.

    Mild
  • What is the effect of Topotecan on the Liver?


    Topotecan is completely safe for the liver.

    Safe
  • What is the effect of Topotecan on the Heart?


    Topotecan is not harmful for the heart.

    Safe


Severe Interaction of Topotecan with Other Drugs

Topotecan should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Topotecan Contraindications

If you are suffering from any of the following diseases, you should not take Topotecan unless your doctor advises you to do so -



Frequently asked Questions about Topotecan

  • Is this Topotecan habit forming or addictive?


    No, there is no any evidence that Topotecan is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Topotecan can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Topotecan only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Topotecan for mental disorders.

    No

Topotecan Interactions with Food and Alcohol

  • Interaction between Food and Topotecan


    Taking Topotecan with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Topotecan


    Due to lack of research, there is no information about the side effects of taking Topotecan with alcohol.

    Unknown


See all substitutes for Topotecan


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Topotecan

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1221-1223

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 866



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