Allopurizol

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Allopurizol Information


Allopurizol Benefits & Uses

Allopurizol is used to treat the following -

Other Benefits

Allopurizol Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 100 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose may increase up to 300 mg
2 - 12 years (Child)
  • Disease: High Uric Acid Levels in the Blood
  • Before or After Meal: After Meal
  • Single Maximum Dose: 100 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Allopurizol Related Warnings

  • Is the use of Allopurizol safe for pregnant women?


    Pregnant women may get severe side effects after taking Allopurizol. If you are pregnant, do not take Allopurizol without a doctor's advice.

    Severe
  • Is the use of Allopurizol safe during breastfeeding?


    Allopurizol has been seen to have minimal side effects on breastfeeding women.

    Mild
  • What is the effect of Allopurizol on the Kidneys?


    Allopurizol can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Allopurizol on the Liver?


    There may be an adverse effect on the liver after taking Allopurizol. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Allopurizol on the Heart?


    Allopurizol is rarely harmful for the heart.

    Mild

Severe Interaction of Allopurizol with Other Drugs

Allopurizol should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Allopurizol Contraindications

If you are suffering from any of the following diseases, you should not take Allopurizol unless your doctor advises you to do so -


Frequently asked Questions about Allopurizol

  • Is this Allopurizol habit forming or addictive?


    No, you will not get addicted to Allopurizol.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Allopurizol since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Yes, but consume Allopurizol only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Allopurizol for mental disorders.

    No

Allopurizol Interactions with Food and Alcohol

  • Interaction between Food and Allopurizol


    Allopurizol may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.

    Mild
  • Interaction between Alcohol and Allopurizol


    Taking alcohol with Allopurizol can be dangerous.

    Severe

Frequently asked Questions about Allopurizol

Question about 5 years ago

Can Allopurizol cause constipation?

Dr. Manju Shekhawat MBBS , General Physician

No, Allopurizol does not cause constipation in the patients who are taking this drug. However, if you are experiencing constipation after taking this drug may be due to other medical conditions, then inform your doctor and take precautionary methods such as eating fibrous foods and drink plenty of water to avoid constipation.

Question almost 5 years ago

Can Allopurizol cause diarrhoea?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Yes, Allopurizol has been reported to causes diarrhoea but this occurs in those cases who are taking more than the recommended doses. Drink plenty of fluids while you are taking this medicine. If you are experiencing severe diarrhoea after taking this drug, discuss it with your doctor immediately without any further delay.

Question over 5 years ago

How does Allopurizol work?

Dr. Anand Singh MBBS , General Physician

Allopurizol contains allopurinol that belongs to the class of drugs known as xanthine oxidase inhibitors. It works by inhibiting the xanthine oxidase enzyme (Responsible for uric acid production in our body) that lead to disruption in the biosynthesis of uric acid due to which its abnormally high levels are decreased in the body. The decreased levels of uric acid prevent the formation of uric acid crystals and calcium oxalate crystals. Hence, in this way, it prevents from gout.

Question about 5 years ago

Can I discontinue Allopurizol on my own without doctors advice?

Dr. Sameer Awadhiya MBBS , Pediatrics

No, Allopurizol should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.

Question about 5 years ago

Is Allopurizol safe to use?

Dr. Haleema Yezdani MBBS , General Physician

Yes, Allopurizol is safe to use, if taken in a prescribed amount for a specified time as advised by the doctor. However, few side effects have been observed at a regular dose such as rash, nausea, and vomiting. Do not hesitate to inform your doctor if you are facing any of the above side effects.


See all substitutes for Allopurizol


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyloprim ® (allopurinol)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 216-217

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 125-127

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