Dufaximin

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Dufaximin Information

Dufaximin is a prescription drug, available for use as Tablet. It is primarily used for the treatment of Hepatic Encephalopathy. Dufaximin also has some secondary and off-label uses. These are listed below.

Medical history of the patient along with age and gender determines the dosage of Dufaximin. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.

Dufaximin also has some side effects, the most common being Flatulence, Bloating or fullness, Constipation. While these are the most often observed Dufaximin side effects, there are can be others also. These have been listed below. Usually, these side effects of Dufaximin go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

In addition, Dufaximin's effect is Severe during pregnancy and Severe for lactating mothers. Further, the section on Dufaximin related warnings talks about Dufaximin's effects on the liver, heart and kidney.

Some other conditions that can be affected by Dufaximin are listed in the contraindications section below.

Additionally, Dufaximin may also adversely react with other medicines. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Dufaximin is considered safe while driving, and is addictive.



Dufaximin Benefits & Uses

Dufaximin is used to treat the following -

Main Benefits

Other Benefits

Dufaximin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor

Dufaximin Related Warnings

  • Is the use of Dufaximin safe for pregnant women?


    Pregnant women may get severe side effects after taking Dufaximin. If you are pregnant, do not take Dufaximin without a doctor's advice.

    Severe
  • Is the use of Dufaximin safe during breastfeeding?


    Dufaximin may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Dufaximin on the Kidneys?


    Using Dufaximin does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Dufaximin on the Liver?


    Dufaximin is rarely harmful for the liver.

    Mild
  • What is the effect of Dufaximin on the Heart?


    Using Dufaximin does not have any harmful effects on the heart.

    Safe


Severe Interaction of Dufaximin with Other Drugs

Dufaximin should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Dufaximin Contraindications

If you are suffering from any of the following diseases, you should not take Dufaximin unless your doctor advises you to do so -



Frequently asked Questions about Dufaximin

  • Is this Dufaximin habit forming or addictive?


    No, you will not get addicted to Dufaximin.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Dufaximin since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Dufaximin should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Dufaximin cannot treat any kind of mental disorder.

    No

Dufaximin Interactions with Food and Alcohol

  • Interaction between Food and Dufaximin


    Taking Dufaximin with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Dufaximin


    No research has been done on this till date. Therefore, it is not known what the effect of taking Dufaximin with alcohol will be.

    Unknown


Frequently asked Questions about Dufaximin

Question about 5 years ago

Is Dufaximin safe to use?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Yes, Dufaximin is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as dizziness, nausea, and vomiting. If you experience above-mentioned side effects after taking this drug then inform your doctor and follow his/her instructions.

Question almost 5 years ago

Does Dufaximin cause weight gain?

Dr. Haleema Yezdani MBBS , General Physician

No, Dufaximin does not cause weight gain. It has not been reported by the patients who are taking this drug but Dufaximin has been reported to cause weight loss in a few patients with travelers’ diarrhea. If you notice any unusual rapid weight changes after taking this drug then discuss with it your doctor and follow his/her instructions.

Question almost 5 years ago

Can Dufaximin cause headache?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Yes, Dufaximin might cause a headache. It is a rare side effect of this drug. However, the exact cause of a headache is still unknown. If you experience a severe headache after taking this drug, take a mild painkiller, apply balm and take rest even after this if the pain does not subside then discuss with your doctor without any further delay.

Question over 4 years ago

Is Dufaximin helpful in treating irritable bowel syndrome (IBS)?

Dr. Chinmaya Bal MBBS , General Physician

Yes, Dufaximin is used in the treatment of irritable bowel syndrome with diarrhea (IBS-D). It has been found very effective for IBS-D. Dufaximin is given three times a day up to 14 days in patients of irritable bowel syndrome with diarrhea.

Question about 5 years ago

How long can I safely take Dufaximin?

Dr. Suhas Bhargav MBBS , General Physician

Usually, Dufaximin is given for short-term treatment 2 -14 days which might vary depending on the patient's medical condition. Take Dufaximin as directed by your doctor to ensure complete eradication of infection. Do not take this medicine longer than prescribed duration to avoid bacterial resistance.



See all substitutes for Dufaximin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xifaxan® (rifaximin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 681-683

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1096-1097

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