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Metadrate, a prescription drug, is manufactured in various forms such as Suspension, Tablet. The alternative uses of Metadrate have also been explained below.
Medical history of the patient along with age and gender determines the dosage of Metadrate. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. This information has been provided in detail in the dosage section.
Metadrate also has some side effects, the most common being Diarrhoea, Drowsiness, Insomnia. Besides the aforementioned side effects, there are other adverse effects of Metadrate as well, which are listed below. Normally, these side effects of Metadrate are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.
In addition, Metadrate's effect is Unknown during pregnancy and Safe for lactating mothers. In addition, Metadrate's effects on the liver, heart and kidney are discussed below in the Metadrate related warnings section.
Metadrate is contraindicated in people with pre-existing medical conditions like Gastrointestinal Bleeding, Kidney Disease as it can result in adverse effects. The section on Metadrate contraindications lists all such conditions.
Drug interactions for Metadrate have been reported in the medical literature. See below for a complete list.
In addition to these precautions, you may also note that Metadrate is safe while driving, and is is addictive in nature.
Metadrate is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
Based on research, the following side effects have been observed when Metadrate is used -
Severe
Moderate
Mild
Common
Unknown
Is the use of Metadrate safe for pregnant women?
Side effects of Metadrate during pregnancy are not known because scientific research on this topic hasn't been done.
Is the use of Metadrate safe during breastfeeding?
Metadrate does not show any harmful effects in lactating women.
What is the effect of Metadrate on the Kidneys?
Metadrate may have mild side effects on the kidneys.
What is the effect of Metadrate on the Liver?
Metadrate does not damage the liver.
What is the effect of Metadrate on the Heart?
Metadrate is not harmful for the heart.
Metadrate should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Metadrate unless your doctor advises you to do so -
Is this Metadrate habit forming or addictive?
No, you will not get addicted to Metadrate.
Interaction between Food and Metadrate
Taking Metadrate with food does not cause any problems.
Interaction between Alcohol and Metadrate
Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Metadrate.
Metadrate contains metoclopramide which is an antiemetic agent that prevents from nausea and vomiting by inhibiting certain chemical messengers (neurotransmitters such as dopamine and serotonin) in the brain. In diabetic gastroparesis, Metadrate works by increasing gastrointestinal motility and fasting the gastric emptying process. In gastroesophageal reflux disease (GERD), Metadrate works by increasing lower esophageal sphincter (LES) tone which prevents the gastric contents to reach food pipe that causes symptoms associated with GERD.
No, Metadrate should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.
The dose of Metadrate may vary from case to case basis depending on the medical condition of the patient. You are advised to take it as per your doctor's instructions. The oral form of Metadrate has to be taken before a meal for better outcomes. Precautions must be taken in patients with heart diseases, and improper liver or kidney function.
Yes Metadrate can be taken with tramadol. Tramadol does not appear to interfere with the efficacy of Metadrate. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
Yes, Metadrate can be taken with omeprazole. No clinically significant drug interaction has been reported between them. However, if you feel any discomfort after taking this drug along with omeprazole then do not hesitate to inform your doctor.
This medicine data has been created by -
B.Pharma, Pharmacy
7 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Reglan® (metoclopramide)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 664-667
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 655
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 799-800