Microshield PVP

Yes, Microshield PVP is suitable for a fungal infection. Fungal infections can be managed by using a topical treatment and adhering to it, by washing the skin with slightly warm water and an antifungal soap or a wash, by keeping the skin dry, by daily washing the towel, bedsheet and the clothes, by not wearing tight clothes, etc.

Microshield PVP is used as an antiseptic and a disinfectant. It is used for the treatment of contaminated wounds, pre-operative preparation of mucous membranes and skin and disinfection of the equipment. Microshield PVP is also available as a sterile solution for prepping eyelids, cheek and brows and ocular region irrigation (cleansing of eyes).

Microshield PVP is also known as an iodophor, meaning that povidone is a carrier of iodine. Iodine kills the microbes as it acts as the active molecule. Once released from the complex, the free iodine penetrates into the cell walls of the microorganisms and inhibits the synthesis and structures of proteins and nucleic acids. Even though the complete mechanism is not understood, it is hypothesized that iodine disrupts the vital bacterial structures and mechanisms, denaturing and deactivating the bacteria. In-vitro studies have also suggested that iodine decreases the inflammation caused by the pathogens and host cells.

Yes, Microshield PVP is used for open wounds since last few decades. It remains a favorite agent for use as an antiseptic and as a wound-healing agent because of its safety, tolerability, and efficacy. Microshield PVP has a broad spectrum of activity, has reduced cell toxicity, low incidence of resistance has anti-inflammatory property, and is able to penetrate biofilms (cluster of microorganisms attached to the cell surface).

Yes, there have been reports of Microshield PVP causing acute kidney injury. Microshield PVP is widely used as an antiseptic and as a preoperative and postoperative surgical scrub. Its main moiety is iodine which is effective against yeast, fungi, bacteria, and protozoans. However, it is also known to cause toxicity, resulting in acute kidney injury in a person who ingested it, in people in whom it has been used topically, etc.