Olanzapine

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  • Manufactured by: Jan Aushadhi
  • Contains / Salt: Olanzapine
  • Storage: translation missing: en.0

Olanzapine Information

Olanzapine is a prescription medicine. Primarily, it is used for the treatment of Schizophrenia. Secondary and off-label uses of Olanzapine have also been mentioned below.

The right dosage of Olanzapine depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.

Apart from the aforementioned side effects, Olanzapine can also lead to other problems, which have been listed below. Normally, these side effects of Olanzapine are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Olanzapine's effect during pregnancy is Moderate and Severe while nursing. In addition, Olanzapine's effects on the liver, heart and kidney are discussed below in the Olanzapine related warnings section.

Olanzapine is not recommended if you suffer from certain medical conditions as it can have adverse effects. Tardive Dyskinesia, Depression are examples of such conditions. Other contraindications of Olanzapine have been discussed in the sections ahead.

Additionally, Olanzapine may also adversely react with other medicines. See below for a complete list.

You should also be aware that Olanzapine is not safe while driving, and is not addiction.


Olanzapine Benefits & Uses

Olanzapine is used to treat the following -

Main Benefits

Other Benefits

Olanzapine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 10 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 5 - 20 mg/day
Geriatric
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 5 - 10 mg/day
13 - 18 years (Adolescent)
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 5 - 10 mg/day

Olanzapine Side Effects

Based on research, the following side effects have been observed when Olanzapine is used -

Moderate

  • Orthostatic Hypotension (Sudden Lowering of Blood Pressure on Standing)
  • Euphoria

Mild

Olanzapine Related Warnings

  • Is the use of Olanzapine safe for pregnant women?


    Olanzapine can have harmful effects in pregnant women. If you experience any discomfort after using Olanzapine, then discontinue the use and take your doctor's advice.

    Moderate
  • Is the use of Olanzapine safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Olanzapine. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Olanzapine on the Kidneys?


    Olanzapine is not harmful for kidneys.

    Safe
  • What is the effect of Olanzapine on the Liver?


    Olanzapine may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Olanzapine on the Heart?


    Olanzapine has very mild side effects on the heart.

    Mild

Severe Interaction of Olanzapine with Other Drugs

Olanzapine should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate


Olanzapine Contraindications

If you are suffering from any of the following diseases, you should not take Olanzapine unless your doctor advises you to do so -


Frequently asked Questions about Olanzapine

  • Is this Olanzapine habit forming or addictive?


    Olanzapine is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Olanzapine. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Olanzapine is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, in many cases, taking Olanzapine can help with mental disorders.

    Yes

Olanzapine Interactions with Food and Alcohol

  • Interaction between Food and Olanzapine


    Taking Olanzapine with some specific foods may delay its effect. Talk to your doctor about this.

    Mild
  • Interaction between Alcohol and Olanzapine


    Taking alcohol with Olanzapine can be dangerous.

    Severe

Frequently asked Questions about Olanzapine

Question over 4 years ago

Can Olanzapine help with OCD (obsessive-compulsive disorder)?

Dr. Madhur Anand MBBS, MS , General Surgery

Yes, Olanzapine might help with OCD (obsessive-compulsive disorder) in those patients who are unresponsive to the conventional treatment. Scientific data suggests that it might improve the mood symptoms in the treatment of unresponsive OCD patients.

Question over 4 years ago

Does Olanzapine treat anxiety?

Dr. Ajay Kumar. MBBS, MD , Psychiatry, General Physician, Infectious Disease, Sexology, Internal Medicine, Venereology, Diabetology

Yes, Olanzapine may be helpful for treating anxiety in those individuals who do not respond to conventional therapy. However, this drug is only approved for the treatment of schizophrenia, Bipolar I Disorder (manic or mixed episodes) and to control the agitation associated with schizophrenia and mania.

Question almost 5 years ago

Does Olanzapine cause drowsiness?

Dr. Ramraj MBBS , Other

Yes, Olanzapine may cause drowsiness or sedation. It is a common side effect of this drug. It occurs because this drug affects the levels of chemical messengers in your brain. You are advised not to drive any vehicle or operate heavy machinery after taking this drug to avoid accidents

Question over 4 years ago

Can I take Olanzapine and klonopin together?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

No, Olanzapine and Klonopin (clonazepam) should not be taken together at the same time because Olanzapine is a derivative of benzodiazepines and clonazepam belongs to the benzodiazepine class as well. Using both of these drugs together can cause increased sedation. If you are taking them together then you are advised to consult with your doctor before consuming these two medicines together.

Question almost 5 years ago

Can Olanzapine cause mania?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Yes, Olanzapine might cause mania. It is a rare side effect of this drug and the exact cause behind mania is unknown. If you are experiencing any unusual changes in personality, behavior (aggression), and thoughts. Then you are advised to discuss it with your doctor without any further delay.


See all substitutes for Olanzapine


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 932-934

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 442

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyprexa (olanzapine)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyprexa Intramuscular (olanzapine)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyprexa Relprevv (olanzapine)

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