Ondapil

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10 TABLET 1 Strip ₹ 45
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  • Contains / Salt: Ondansetron (4 mg)
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Ondapil Information

Ondapil is a prescription medicine that is available as a Tablet. It is primarily used for the treatment of Nausea and Vomiting.

The correct dosage of Ondapil depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.

While these are the most often observed Ondapil side effects, there are can be others also. These have been listed below. Such side effects of Ondapil normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

In addition, Ondapil's effect is Safe during pregnancy and Mild for lactating mothers. It is important to know if Ondapil has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Ondapil related warnings section.

Ondapil is not recommended if you suffer from certain medical conditions as it can have adverse effects. Heart Disease, Calcium Deficiency, Potassium Deficiency are examples of such conditions. Some other conditions that can be affected by Ondapil are listed in the contraindications section below.

Drug reaction of Ondapil with other medicines has been reported. See below for a complete list.

You should also be aware that Ondapil is not safe while driving, and is not addiction.



Ondapil Benefits & Uses

Ondapil is used to treat the following -

Ondapil Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 5 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 4 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 5 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy


Ondapil Side Effects

Based on research, the following side effects have been observed when Ondapil is used -

Moderate

Mild

Ondapil Related Warnings

  • Is the use of Ondapil safe for pregnant women?


    Ondapil is safe for pregnant women.

    Safe
  • Is the use of Ondapil safe during breastfeeding?


    Side effects of Ondapil on breastfeeding women are very mild.

    Mild
  • What is the effect of Ondapil on the Kidneys?


    Ondapil does not damage the kidneys.

    Safe
  • What is the effect of Ondapil on the Liver?


    Ondapil may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Ondapil on the Heart?


    You may experience side effects on your heart after taking Ondapil. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

    Moderate


Severe Interaction of Ondapil with Other Drugs

Ondapil should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Ondapil Contraindications

If you are suffering from any of the following diseases, you should not take Ondapil unless your doctor advises you to do so -



Frequently asked Questions about Ondapil

  • Is this Ondapil habit forming or addictive?


    Forming a habit of Ondapil has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Ondapil as you may feel sleepy.

    Dangerous
  • Is it safe?


    Ondapil should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Ondapil for mental disorders.

    No

Ondapil Interactions with Food and Alcohol

  • Interaction between Food and Ondapil


    Taking Ondapil with food is safe.

    Safe
  • Interaction between Alcohol and Ondapil


    Consumption of alcohol and Ondapil together may have severe effects on your health.

    Severe


Frequently asked Questions about Ondapil

Question about 5 years ago

How does Ondapil work?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Ondapil belongs to a class of compounds known as 5 -HT3 receptor antagonists. It blocks the action of serotonin completely at the 5-HT3 receptor sites present in our brain (vomiting centre) which provides relief to the patient from nausea and vomiting.

Question about 5 years ago

Can Ondapil be taken for motion sickness?

Dr. Ajay Kumar MBBS, MD , General Physician

No, Ondapil is not found to be effective against motion sickness. It prevents vomiting due to chemotherapeutic drugs and radiation. Motion sickness is the disturbance of the inner ear caused by a lot of motion. It can be prevented by not taking too much food or too many drinks or alcohol just before the travel. One should also avoid food with very strong odours. One should avoid reading while traveling. One should also sit in the direction of the travel. One should sit in the front. Open a vent of fresh air and try to be relaxed while traveling. 

Question almost 5 years ago

Does Ondapil cause drowsiness?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, Ondapil may cause drowsiness because this drug has been reported to induce sleep. Ensure you do not drive or do some high precision work. To avoid excessive drowsiness with this medicine you are encouraged to take adequate night-time sleep, keeping distractions out of the bedroom, going to sleep and getting up at consistent times, eating light at lunchtime, putting in some form of a physical activity, avoiding taking naps during the day, and avoiding alcohol at night.

Question about 5 years ago

Is Ondapil safe for children?

Dr. R.K Singh MBBS , Diabetology

Yes, Ondapil is safe to be used in children from 6 months to 12 years of age. Apart from preventing nausea and vomiting related to chemotherapy and radiation, Ondapil can be used in this population group for managing acute gastritis. Acute gastritis presents itself as a self-limited infection with vomiting leading to dehydration and electrolyte imbalances. Always check with a child specialist and do not administer this drug yourself.

Question over 4 years ago

Can Ondapil be taken with pantoprazole?

Dr. Ramraj Meena MBBS , General Physician

Yes, Ondapil can be taken with pantoprazole as there are no records of any drug interaction. Pantoprazole is a proton pump inhibitor which is used for treating acidity. Acidity can be managed by avoiding eating acidic and spicy foods, avoiding smoking, and avoiding sleep within 3 hours of taking meals.



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)



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