Onset (Zota)

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Onset (Zota) Information

Onset (Zota) is a commercial drug that is prescribed in the form of Injection. It is typically used for the treatment of Nausea and Vomiting.

Medical history of the patient along with age and gender determines the dosage of Onset (Zota). The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.

While these are the most often observed Onset (Zota) side effects, there are can be others also. These have been listed below. Such side effects of Onset (Zota) normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Onset (Zota) has a Safe effect for pregnant women and Mild effect on lactating mothers. Further, the section on Onset (Zota) related warnings talks about Onset (Zota)'s effects on the liver, heart and kidney.

Onset (Zota) can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Onset (Zota) in conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency. Other conditions have been mentioned below in the Onset (Zota) contraindications section.

Additionally, Onset (Zota) may also adversely react with other medicines. A complete list of these interactions is given below.

In addition to the above precautions for Onset (Zota), it is important to know that it is not safe while driving, and is not habit-forming.


Onset (Zota) Benefits & Uses

Onset (Zota) is used to treat the following -

Onset (Zota) Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Geriatric
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
13 - 18 years (Adolescent)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
2 - 12 years (Child)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Infant (1 month to 2 years)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy. Given dose older then 6 month

Onset (Zota) Side Effects

Based on research, the following side effects have been observed when Onset (Zota) is used -

Moderate

Mild

Onset (Zota) Related Warnings

  • Is the use of Onset (Zota) safe for pregnant women?


    Onset (Zota) is safe to take during pregnancy.

    Safe
  • Is the use of Onset (Zota) safe during breastfeeding?


    Side effects of Onset (Zota) for breastfeeding are little to none, so you can take it without doctor's advice.

    Mild
  • What is the effect of Onset (Zota) on the Kidneys?


    Using Onset (Zota) does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Onset (Zota) on the Liver?


    There may be an adverse effect on the liver after taking Onset (Zota). If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Onset (Zota) on the Heart?


    You may experience side effects on your heart after taking Onset (Zota). If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

    Moderate

Severe Interaction of Onset (Zota) with Other Drugs

Onset (Zota) should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Onset (Zota) Contraindications

If you are suffering from any of the following diseases, you should not take Onset (Zota) unless your doctor advises you to do so -


Frequently asked Questions about Onset (Zota)

  • Is this Onset (Zota) habit forming or addictive?


    Onset (Zota) is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Onset (Zota), you should not drive or work on any heavy machine, as Onset (Zota) can make you drowsy.

    Dangerous
  • Is it safe?


    Onset (Zota) is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Onset (Zota) is not used to treat mental disorders.

    No

Onset (Zota) Interactions with Food and Alcohol

  • Interaction between Food and Onset (Zota)


    Taking Onset (Zota) with food does not harm your health.

    Safe
  • Interaction between Alcohol and Onset (Zota)


    Taking Onset (Zota) with alcohol can have severely harmful effects on your health.

    Severe

See all substitutes for Onset (Zota)


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)


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