Pilodine

Yes, Pilodine kills bacteria. It exerts its bactericidal effect by invading the cell wall of the bacteria and killing its DNA and denaturing the enzymes.

Yes, there have been reports of Pilodine causing acute kidney injury. Pilodine is widely used as an antiseptic and as a preoperative and postoperative surgical scrub. Its main moiety is iodine which is effective against yeast, fungi, bacteria, and protozoans. However, it is also known to cause toxicity, resulting in acute kidney injury in a person who ingested it, in people in whom it has been used topically, etc.

Yes, Pilodine is used for open wounds since last few decades. It remains a favorite agent for use as an antiseptic and as a wound-healing agent because of its safety, tolerability, and efficacy. Pilodine has a broad spectrum of activity, has reduced cell toxicity, low incidence of resistance has anti-inflammatory property, and is able to penetrate biofilms (cluster of microorganisms attached to the cell surface).

Yes, in rare instances, Pilodine may cause allergy. It could be manifested as a rash, an itch, a swelling around the mouth, on lips, tongue or throat, wheezing, sneezing, etc. If you develop any of these symptoms, talk to your doctor immediately. 

Yes, rarely, a chemical burn can develop from Pilodine. It develops when during a surgical procedure, Pilodine is used, however, it doesn't dry and starts dripping, and collects in a body part. Symptoms may develop instantly or after a day. It develops because iodine causes irritation, maceration, pressure and then friction. Healing might not require much medical intervention but it causes discomfort, might prolong the hospital stay and expose a person to an infection.