Piorest M is a commercial drug that is prescribed in the form of Tablet. Other than this, Piorest M has some other therapeutic uses, which have been discussed ahead.
The optimal dosage of Piorest M is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.
Common side effects of Piorest M include Stomach Upset, Difficulty urinating, Muscle Ache. While these are the most often observed Piorest M side effects, there are can be others also. These have been listed below. Normally, these side effects of Piorest M are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.
Furthermore, you should know that effect of Piorest M is Moderate for pregnant women and Moderate for women who are breastfeeding. Warnings related to Piorest M's effects on the liver, heart and kidney, if any, have been listed below.
Piorest M is contraindicated in people with pre-existing medical conditions like Congestive Heart Failure (CHF), Anemia, Shock as it can result in adverse effects. Other conditions have been mentioned below in the Piorest M contraindications section.
Drug reaction of Piorest M with other medicines has been reported. See below for a complete list.
In addition to the above precautions for Piorest M, it is important to know that it is safe while driving, and is habit-forming.
Piorest M is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Is the use of Piorest M safe for pregnant women?
Pregnant women may experience moderate side effects from Piorest M. It is best to stop taking Piorest M immediately and inform your doctor if you notice any discomfort.
Is the use of Piorest M safe during breastfeeding?
Women who are breastfeeding can experience some moderate side effects of Piorest M. Immediately discontinue Piorest M if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.
What is the effect of Piorest M on the Kidneys?
Piorest M may have mild side effects on the kidneys.
What is the effect of Piorest M on the Liver?
You may experience side effects on your liver after taking Piorest M. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.
What is the effect of Piorest M on the Heart?
The heart can be affected by Piorest M. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.
Piorest M should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Piorest M unless your doctor advises you to do so -
Is this Piorest M habit forming or addictive?
No, you will not get addicted to Piorest M.
Interaction between Food and Piorest M
There is no information on the effects of taking Piorest M with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Piorest M
Taking [medicine] and alcohol at the same time may lead to mild side effects. Contact your doctor right away if you observe any side effects.
Piorest M works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.
Piorest M can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime.
Yes, Piorest M commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Piorest M with your meal and increase the dose gradually.
Lactic acidosis associated with Piorest M treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Piorest M induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.
Piorest M increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Actos (pioglitazone hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 276-277
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1032-1033