Progesterone Injection - Onxygest 200 Soft Gelatin Capsule (10)

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10 Capsule in 1 Strip
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    Progesterone Information

    Progesterone is a prescription medicine. Primarily, it is used for the treatment of Female Infertility, Hormonal Imbalance. Secondary and off-label uses of Progesterone have also been mentioned below.

    Medical history of the patient along with age and gender determines the dosage of Progesterone. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

    Progesterone also has some side effects, the most common being Back Pain, Increased Glucose level in the blood. Besides the aforementioned side effects, there are other adverse effects of Progesterone as well, which are listed below. Usually, these side effects of Progesterone go away soon, and do not persist beyond the duration of the treatment. However, if these continue for a longer time, consult your doctor right away.

    In addition, Progesterone's effect is Moderate during pregnancy and Moderate for lactating mothers. It is important to know if Progesterone has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Progesterone related warnings section.

    Progesterone is contraindicated in people with pre-existing medical conditions like Liver Disease, Breast Cancer, Cervical Cancer as it can result in adverse effects. Other contraindications of Progesterone have been discussed in the sections ahead.

    Drug reaction of Progesterone with other medicines has been reported. A complete list of these interactions is given below.

    In addition to these precautions, you may also note that Progesterone is safe while driving, and is is addictive in nature.

    Progesterone Benefits & Uses

    Progesterone is used to treat the following -

    Main Benefits

    Other Benefits

    Progesterone Dosage & How to Take

    This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

    Find the right dosage based on disease and age

    Age Group Dosage
    • Disease: Amenorrhea
    • Before or After Meal: As advised by a physician
    • Single Maximum Dose: 10 mg
    • Dosage Route: Parenteral
    • Frequency: 1 daily
    • Course Duration: 10 days
    • Special Instructions: As prescribed by the doctor

    Progesterone Side Effects

    Based on research, the following side effects have been observed when Progesterone is used -


    • Chest Pain
    • Visual Disturbance
    • Anaphylactic reaction
    • Suicidal behavior



    • Rash
    • Headache
    • Dizziness
    • Increased appetite
    • Decreased libido
    • Abdominal distension
    • Drowsiness
    • Nausea or vomiting
    • पेट दर्द
    • Hair Loss
    • Fatigue
    • Acne
    • Diarrhoea
    • Altered menstrual cycle
    • Vaginal discharge
    • Maculopapular rash


    • Back Pain
    • Increased Glucose level in the blood

    Progesterone Related Warnings

    • Is the use of Progesterone safe for pregnant women?

      Progesterone may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Progesterone again without your doctor's advice.

    • Is the use of Progesterone safe during breastfeeding?

      Women who are breastfeeding can experience some moderate side effects of Progesterone. Immediately discontinue Progesterone if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

    • What is the effect of Progesterone on the Kidneys?

      Progesterone rarely affects the kidneys.

    • What is the effect of Progesterone on the Liver?

      You may experience side effects on your liver after taking Progesterone. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

    • What is the effect of Progesterone on the Heart?

      Progesterone has very mild side effects on the heart.


    Severe Interaction of Progesterone with Other Drugs

    Progesterone should not be taken with following medicines due to severe side effects it may cause to patients -




    Progesterone Contraindications

    If you are suffering from any of the following diseases, you should not take Progesterone unless your doctor advises you to do so -

    Frequently asked Questions about Progesterone

    • Is this Progesterone habit forming or addictive?

      Progesterone does not cause addiction.

    • Is it safe to drive or operate heavy machinery when consuming?

      Yes, it is safe to do these activities or work after taking Progesterone as it does not make you drowsy.

    • Is it safe?

      Yes, Progesterone is safe but you must consult your doctor before taking it.

      Safe, but take only on Doctor's advise
    • Is it able to treat mental disorders?

      No, the use of Progesterone in mental disorders is not effective.


    Progesterone Interactions with Food and Alcohol

    • Interaction between Food and Progesterone

      Due to the absence of research, it is difficult to say how Progesterone and food will interact.

    • Interaction between Alcohol and Progesterone

      Due to lack of research, there is no information about the side effects of taking Progesterone with alcohol.


    Frequently asked Questions about Progesterone

    Question over 5 years ago

    Does Progesterone cause weight gain?

    Dr. Sangita Shah MBBS , General Physician

    No, Progesterone helps in reducing the weight by regulating thyroid hormone and maintaining insulin levels. It acts as an anti-inflammatory agent and a natural sleep inducer. Eat healthy meals and indulge in physical activities to keep a check on weight. If you still experience increase in weight discuss with your doctor to investigate underlying causes of your weight gain.

    Question almost 5 years ago

    Does Progesterone cause hair loss?

    Dr. Haleema Yezdani MBBS , General Physician

    Yes, Progesterone has been reported to cause testosterone like side effects such as loss of hair and acne in some patients. Intake of few hormones can actually shrink and damage the hair follicles. if you are experiencing hair loss along with Progesterone seek medical advice instantly.

    Question over 5 years ago

    How does Progesterone work?

    Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

    Progesterone helps in regulating the menstrual cycle. It prepares the uterus for pregnancy. After ovulation every month, it thickens the uterine wall to prepare to receive the fertilized egg, however, if there is no fertilization, the levels of progesterone drop and menstruation begins. In case of fertilization the fertilized egg implants in the uterine wall, progesterone helps maintain the thickness of the uterine wall throughout the duration of pregnancy.

    Question almost 5 years ago

    Can I take Progesterone during periods?

    Dr. Saikat Mukherjee MBBS , General Physician

    If your period starts while taking Progesterone, it is important to continue with the medication till the 14th day. However, the next progesterone cycle should be started after 14 days after the beginning of the flow. In case you feel any discomfort while taking progesterone during your period cycle do not hesitate to inform your doctor. 

    Question almost 5 years ago

    Can I take Progesterone with thyroids medication

    Dr. Sangita Shah MBBS , General Physician

    It is always recommended to take different hormones at a different time to prevent interactions. Thyroid medications are lifelong drugs which when not taken can lead to serious consequences. Space both the hormones in consultation with your gynaecologist.

    See all substitutes for Progesterone

    This medicine data has been created by -

    Vikas Chauhan

    B.Pharma, Pharmacy
    5 Years of Experience


    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prometrium (progesterone)

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