Tacrel

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  • Manufactured by: Zydus Cadila
  • Contains / Salt: Tacrolimus (0.1 % w/w)

Tacrel Information

Tacrel is a prescription drug, available for use as Ointment. Primarily, it is used for the treatment of Liver transplant, Kidney transplant, Heart Transplant. Tacrel also has some secondary and off-label uses. These are listed below.

The correct dosage of Tacrel depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.

Apart from the aforementioned side effects, Tacrel can also lead to other problems, which have been listed below. These side effects of Tacrel are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.

In addition, Tacrel's effect is Moderate during pregnancy and Moderate for lactating mothers. Further, the section on Tacrel related warnings talks about Tacrel's effects on the liver, heart and kidney.

Tacrel is not recommended if you suffer from certain medical conditions as it can have adverse effects. Infections, Diabetes Type 2 are examples of such conditions. Other conditions have been mentioned below in the Tacrel contraindications section.

Additionally, Tacrel may also adversely react with other medicines. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Tacrel is considered safe while driving, and is addictive.


Tacrel Benefits & Uses

Tacrel is used to treat the following -

Main Benefits

Other Benefits

Tacrel Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
Geriatric
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
13 - 18 years (Adolescent)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
2 - 12 years (Child)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice

Tacrel Side Effects

Based on research, the following side effects have been observed when Tacrel is used -

Moderate

Mild

Tacrel Related Warnings

  • Is the use of Tacrel safe for pregnant women?


    Pregnant women may experience moderate side effects from Tacrel. It is best to stop taking Tacrel immediately and inform your doctor if you notice any discomfort.

    Moderate
  • Is the use of Tacrel safe during breastfeeding?


    Breastfeeding women may feel side effects of Tacrel. If you see any side effects, stop taking Tacrel immediately and talk to your doctor. Take Tacrel again, only after your doctor's advice.

    Moderate
  • What is the effect of Tacrel on the Kidneys?


    Kidney can be affected by Tacrel. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.

    Moderate
  • What is the effect of Tacrel on the Liver?


    The liver can be affected by Tacrel. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Tacrel only after medical advice.

    Moderate
  • What is the effect of Tacrel on the Heart?


    There may be severe side effects of Tacrel on your heart. Do not take it unless a doctor says so.

    Severe

Severe Interaction of Tacrel with Other Drugs

Tacrel should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Tacrel Contraindications

If you are suffering from any of the following diseases, you should not take Tacrel unless your doctor advises you to do so -


Frequently asked Questions about Tacrel

  • Is this Tacrel habit forming or addictive?


    Forming a habit of Tacrel has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Tacrel does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

    Safe
  • Is it safe?


    Tacrel should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Tacrel is not used to treat mental disorders.

    No

Tacrel Interactions with Food and Alcohol

  • Interaction between Food and Tacrel


    There isn't any research available on the side effects of taking Tacrel with food.

    Unknown
  • Interaction between Alcohol and Tacrel


    Consult your doctor before consuming alcohol while taking Tacrel as it can have severe side effects.

    Severe

See all substitutes for Tacrel


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prograf® (tacrolimus)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 881

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1165-1167

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prograf® (tacrolimus)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 881

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1165-1167

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