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Valrate, a prescription drug, is manufactured in various forms such as Tablet, Syrup. Epilepsy are some of its major therapeutic uses. Other than this, Valrate has some other therapeutic uses, which have been discussed ahead.
The correct dosage of Valrate depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.
Valrate also has some side effects, the most common being Loss of appetite. Besides the aforementioned side effects, there are other adverse effects of Valrate as well, which are listed below. Normally, these side effects of Valrate are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.
Valrate's effect during pregnancy is Severe and Mild while nursing. Warnings related to Valrate's effects on the liver, heart and kidney, if any, have been listed below.
Valrate can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Valrate in conditions like Depression, Liver Disease. Other conditions have been mentioned below in the Valrate contraindications section.
Drug interactions for Valrate have been reported in the medical literature. See below for a complete list.
Along with the above-mentioned precautions, remember that taking Valrate is considered not safe while driving, and is not addictive.
Valrate is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Is the use of Valrate safe for pregnant women?
Valrate can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Valrate safe during breastfeeding?
Side effects of Valrate for breastfeeding are little to none, so you can take it without doctor's advice.
What is the effect of Valrate on the Kidneys?
Valrate rarely affects the kidneys.
What is the effect of Valrate on the Liver?
Very few cases of side effects of Valrate on the liver have been reported.
What is the effect of Valrate on the Heart?
Valrate is not harmful for the heart.
Valrate should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Valrate unless your doctor advises you to do so -
Is this Valrate habit forming or addictive?
No, there is no any evidence that Valrate is addictive.
Is it safe to drive or operate heavy machinery when consuming?
No, you should not drive or operate heavy machinery after taking Valrate as you may feel sleepy.
Is it safe?
Valrate should be used only after doctor's advice.
Is it able to treat mental disorders?
Yes, Valrate is useful in treating mental disorders.
Interaction between Food and Valrate
Taking Valrate with food is safe.
Interaction between Alcohol and Valrate
Consuming Valrate with alcohol can have many serious effects on your body.
Yes, Valrate causes erectile dysfunction. If you experience erectile dysfunction after taking it, do not stop the drug without consulting your doctor. Discuss with your doctor, he/she will provide you with solutions or prescribe alternative medicines.
Valrate works by relaxing the muscles of the body and suppressing abnormal activity of nerve cells in the brain through an increase in activity of a chemical messenger known as GABA (gamma-aminobutyric acid) by inhibiting the enzymes which are responsible for the catabolism of GABA. It also exerts effect altering the sodium channel in the brain. It also works by stabilizing the potassium channel and cause a direct membrane-stabilizing effect. Thus, providing relief from the seizure and mania associated with bipolar disorder.
Yes, Valrate may make you sleepy because it causes drowsiness, dizziness or sedation. It is a common side effect of this medicine. Do not drive vehicle or operate machinery after taking this medicine.
Yes, Valrate causes low blood pressure (hypotension) in the patients who are taking it. However, the exact cause behind this is unknown. If you are experiencing dizziness or lightheadedness which is a symptom of low blood pressure after taking this drug, then please consult with your doctor.
Yes, Valrate can be taken with ibuprofen. No harmful interaction has been reported between them. However, it doesn't mean that no interaction exists between them. Always consult your doctor before taking these two medicines at the same time.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Depakene (valproic acid)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 417-418