Xifapill

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Xifapill Information

Xifapill, a prescription drug, is manufactured in various forms such as Tablet. Hepatic Encephalopathy are some of its major therapeutic uses. Xifapill also has some secondary and off-label uses. These are listed below.

The correct dosage of Xifapill depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.

The side effects typically associated with Xifapill include Flatulence, Bloating or fullness, Constipation. Apart from the aforementioned side effects, Xifapill can also lead to other problems, which have been listed below. Such side effects of Xifapill normally do not last long and go away once the treatment is completed. However, if these continue for a longer time, consult your doctor right away.

It is also important to note that Xifapill has a Severe effect for pregnant women and Severe effect on lactating mothers. Further, the section on Xifapill related warnings talks about Xifapill's effects on the liver, heart and kidney.

Other conditions have been mentioned below in the Xifapill contraindications section.

Drug interactions for Xifapill have been reported in the medical literature. A complete list of these interactions is given below.

You should also be aware that Xifapill is safe while driving, and is addiction.


Xifapill Benefits & Uses

Xifapill is used to treat the following -

Main Benefits

Other Benefits

Xifapill Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 200 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor

Xifapill Side Effects

Based on research, the following side effects have been observed when Xifapill is used -

Moderate

  • Increased Liver Enzymes

Mild

Common

Xifapill Related Warnings

  • Is the use of Xifapill safe for pregnant women?


    Xifapill should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Xifapill safe during breastfeeding?


    Xifapill may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Xifapill on the Kidneys?


    Using Xifapill does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Xifapill on the Liver?


    Very few cases of side effects of Xifapill on the liver have been reported.

    Mild
  • What is the effect of Xifapill on the Heart?


    Xifapill is not harmful for the heart.

    Safe

Severe Interaction of Xifapill with Other Drugs

Xifapill should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate


Xifapill Contraindications

If you are suffering from any of the following diseases, you should not take Xifapill unless your doctor advises you to do so -


Frequently asked Questions about Xifapill

  • Is this Xifapill habit forming or addictive?


    No, there is no any evidence that Xifapill is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, it is safe to do these activities or work after taking Xifapill as it does not make you drowsy.

    Safe
  • Is it safe?


    Yes, Xifapill is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Xifapill cannot treat any kind of mental disorder.

    No

Xifapill Interactions with Food and Alcohol

  • Interaction between Food and Xifapill


    You can take Xifapill with food.

    Safe
  • Interaction between Alcohol and Xifapill


    No research has been done on this till date. Therefore, it is not known what the effect of taking Xifapill with alcohol will be.

    Unknown

Frequently asked Questions about Xifapill

Question about 6 years ago

Can I take Xifapill with loperamide?

Dr. MBBS , Pediatrics, Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

Yes, Xifapill can be taken with loperamide. Loperamide does not appear to interfere with the efficacy of Xifapill. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

Question about 7 years ago

Can I take Xifapill without consulting a doctor?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

No, Xifapill is a prescription drug and an antibiotic, hence do not take this drug without consulting doctor to avoid bacterial resistance and unpleasant side effects. It can be harmful for patients to take this medicine without the doctor's advice.

Question almost 7 years ago

Does Xifapill cause fatigue?

Dr. MBBS , Pediatrics, Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

Rarely, Xifapill causes fatigue. It is an uncommon side effect of this drug. However, the exact cause of fatigue is unknown. If you experience tiredness after taking this drug, then try to take some rest even after that if you feel excessive tiredness then do discuss it with your doctor.

Question over 6 years ago

Does Xifapill kill H pylori?

Dr. Suhas Bhargav MBBS , General Physician

Xifapill in combination with other antibiotics might be used to eradicate Helicobacter pylori (H. pylori) but it is generally not used and not approved for the treatment of the infection caused by H. pylori.

Question about 7 years ago

How long can I safely take Xifapill?

Dr. Suhas Bhargav MBBS , General Physician

Usually, Xifapill is given for short-term treatment 2 -14 days which might vary depending on the patient's medical condition. Take Xifapill as directed by your doctor to ensure complete eradication of infection. Do not take this medicine longer than prescribed duration to avoid bacterial resistance.


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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xifaxan® (rifaximin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 681-683

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1096-1097

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xifaxan® (rifaximin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 681-683

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1096-1097

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