Morphine

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Morphine Information

Morphine is a prescription medicine. It is primarily used for the treatment of Pain. The alternative uses of Morphine have also been explained below.

The right dosage of Morphine depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.

Apart from the aforementioned side effects, Morphine can also lead to other problems, which have been listed below. Normally, these side effects of Morphine are not long lasting and go away when the treatment is finished. However, if these continue for a longer time, consult your doctor right away.

In addition, Morphine's effect is Moderate during pregnancy and Moderate for lactating mothers. Warnings related to Morphine's effects on the liver, heart and kidney, if any, have been listed below.

Morphine can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Morphine in conditions like Asthma, COPD (Chronic Obstructive Pulmonary Disease), Liver Disease. Other conditions have been mentioned below in the Morphine contraindications section.

Drug reaction of Morphine with other medicines has been reported. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Morphine is considered not safe while driving, and is not addictive.



Morphine Benefits & Uses

Morphine is used to treat the following -

Main Benefits

Other Benefits

  • Tetralogy of Fallot

Morphine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Pain
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg
  • Dosage Route: Parenteral
  • Frequency: 4 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose range: 5 to 20 mg every 4 hours as needed, SC dose are also same
Geriatric
  • Disease: Pain
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg
  • Dosage Route: Parenteral
  • Frequency: 4 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose range: 5 to 20 mg every 4 hours as needed, SC dose are also same
Neonates (0 to 1 month)
  • Disease: Tetralogy of Fallot
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 1.2 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 4 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: Given at the rate of 0.005-0.03 mg/kg/hr
Infant (1 month to 2 years)
  • Disease: Tetralogy of Fallot
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.2 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 4 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: Take as needed, dose of SC are also same
2 - 12 years (Child)
  • Disease: Tetralogy of Fallot
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.2 mg/kg
  • Dosage Route: Oral
  • Frequency: 4 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: Take as needed, Dose of SC are also same
13 - 18 years (Adolescent)
  • Disease: Pain
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg
  • Dosage Route: Parenteral
  • Frequency: 4 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: administered slowly over 4 to 5 minutes, Dose range: 2.5 to 10 mg

Morphine Related Warnings

  • Is the use of Morphine safe for pregnant women?


    Morphine may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Morphine again without your doctor's advice.

    Moderate
  • Is the use of Morphine safe during breastfeeding?


    If you are breastfeeding, you may experience some harmful effects of Morphine. In case you experience any of these, discontinue its use until you consult your doctor.

    Moderate
  • What is the effect of Morphine on the Kidneys?


    Using Morphine does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Morphine on the Liver?


    Morphine is rarely harmful for the liver.

    Mild
  • What is the effect of Morphine on the Heart?


    Side effects of Morphine rarely affect the heart.

    Mild


Severe Interaction of Morphine with Other Drugs

Morphine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Morphine Contraindications

If you are suffering from any of the following diseases, you should not take Morphine unless your doctor advises you to do so -



Frequently asked Questions about Morphine

  • Is this Morphine habit forming or addictive?


    Morphine can be addictive. You should not take it without medical advice.

    Yes
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Morphine. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Morphine should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Morphine cannot treat any kind of mental disorder.

    No

Morphine Interactions with Food and Alcohol

  • Interaction between Food and Morphine


    Taking Morphine with food is safe.

    Safe
  • Interaction between Alcohol and Morphine


    Consumption of alcohol and Morphine together may have severe effects on your health.

    Severe


See all substitutes for Morphine


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 875-878

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 469-474

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Morphine sulfate (morphine sulfate)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Morphine sulfate (morphine sulfate)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Morphine sulfate (morphine sulfate)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Morphabond Er™ (morphine sulfate)

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