Pemetrexed Benefits & Uses

Pemetrexed is used to treat the following -

Other Benefits

Non-Small Cell Lung Cancer

Pemetrexed Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Head and neck cancer Before or After Meal: As advised by a physician Single Maximum Dose: 830 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: 500 mg/m² IV over 10 minutes on Day 1 of each 21-days cycle, given in combination with cisplatin
Geriatric	Disease: Head and neck cancer Before or After Meal: As advised by a physician Single Maximum Dose: 830 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: 500 mg/m² IV over 10 minutes on Day 1 of each 21-days cycle, given in combination with cisplatin

Pemetrexed Side Effects

Based on research, the following side effects have been observed when Pemetrexed is used -

Severe

Nausea or vomiting
Loss of appetite
Pharyngitis
Stomatitis (Inflammation of the mouth)
Hair Loss
Reduced blood platelets
Rash
Fatigue
Anemia (Read More - Home Remedies for Anaemia)
Diarrhoea
Decreased white blood cell count (neutrophils)
Neuropathy

Moderate

Peripheral Edema
Hypertension
Chest Pain
Constipation (Read More - Home remedies for constipation)

Mild

Headache
Cough
Dizziness
Insomnia
Fever (Read More - Home remedies for fever)
Itching or burning
पेट दर्द
Urticaria

Pemetrexed Related Warnings

Is the use of Pemetrexed safe for pregnant women?

Pemetrexed shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

Severe
Is the use of Pemetrexed safe during breastfeeding?

Pemetrexed should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

Severe
What is the effect of Pemetrexed on the Kidneys?

Pemetrexed can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate
What is the effect of Pemetrexed on the Liver?

Pemetrexed is completely safe for the liver.

Safe
What is the effect of Pemetrexed on the Heart?

Pemetrexed is not harmful for the heart.

Safe

Severe Interaction of Pemetrexed with Other Drugs

Pemetrexed should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Adalimumab

Leflunomide

Clozapine

Etanercept

Moderate

Warfarin

Aspirin

Pemetrexed Contraindications

If you are suffering from any of the following diseases, you should not take Pemetrexed unless your doctor advises you to do so -

Kidney Disease
Neutropenia
Pneumonitis
Infertility

Frequently asked Questions about Pemetrexed

Is this Pemetrexed habit forming or addictive?

Pemetrexed does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should do not do anything that requires concentration and attention as the Pemetrexed can make you feel drowsy.

Dangerous
Is it safe?

Pemetrexed should be used only after doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Pemetrexed is not used to treat mental disorders.

No

Pemetrexed Interactions with Food and Alcohol

Interaction between Food and Pemetrexed

Taking Pemetrexed with food does not harm your health.

Safe
Interaction between Alcohol and Pemetrexed

Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Pemetrexed.

Unknown

See all substitutes for Pemetrexed

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 999-1000

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 863

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Alimta (pemetrexed disodium)

Pemetrexed Injection - Pempro 100 Injection

Pemetrexed Information