Amfosted

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1 Injection in 1 Vial Out of Stock
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Amfosted Information

Amfosted Injection is a cytoprotective agent used primarily to reduce the harmful side effects of certain cancer treatments. It protects healthy tissues from the toxic effects of chemotherapy and radiation while allowing these treatments to target cancer cells effectively. Amifostine Injection is indicated for:

Protection During Chemotherapy : Used to prevent kidney damage (nephrotoxicity) in patients undergoing cisplatin-based chemotherapy for advanced cancers.

Protection During Radiation Therapy : Reduces dry mouth (xerostomia) in patients receiving radiation therapy for head and neck cancers.

Amifostine is a prodrug that is converted into its active form by the enzyme alkaline phosphatase, which is more abundant in healthy cells than in tumor cells. This selective activation allows the drug to protect normal tissues from damage caused by free radicals generated during chemotherapy or radiation therapy.


Amfosted Benefits & Uses

Amfosted is used to treat the following -

Main Benefits

Other Benefits

Amfosted Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 500 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Before radiation therapy
Geriatric
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 500 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: before radiation therapy

Amfosted Side Effects

Based on research, the following side effects have been observed when Amfosted is used -

Mild

Common

  • Nausea or vomiting

Amfosted Related Warnings

  • Is the use of Amfosted safe for pregnant women?


    Unknown
  • Is the use of Amfosted safe during breastfeeding?


    Unknown
  • What is the effect of Amfosted on the Kidneys?


    Mild
  • What is the effect of Amfosted on the Liver?


    Safe
  • What is the effect of Amfosted on the Heart?


    Mild

Severe Interaction of Amfosted with Other Drugs

Amfosted should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate


Amfosted Contraindications

If you are suffering from any of the following diseases, you should not take Amfosted unless your doctor advises you to do so -


Frequently asked Questions about Amfosted

  • Is this Amfosted habit forming or addictive?


    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Dangerous
  • Is it safe?


    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No

Amfosted Interactions with Food and Alcohol

  • Interaction between Food and Amfosted


    Mild
  • Interaction between Alcohol and Amfosted


    Mild

See all substitutes for Amfosted


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
7 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ethyol® (amifostine)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 876

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 133-134


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1 Injection in 1 Vial