Spironolactone + Metolazone

Yes, Spironolactone + Metolazone can raise blood sugar levels slightly in diabetic patients. However, the exact cause behind this is unknown but it is presumed that Spironolactone + Metolazone decreases the sensitivity of insulin towards glucose which causes a rise in blood sugar levels. So, if you have diabetes keep a check on your blood sugar levels and in case of a sudden spike in sugar levels take blood glucose lowering medicines to manage your diabetes.

No, use of Spironolactone + Metolazone does not cause hair loss in the patients who are taking it. However, if you notice any unusual hair loss then consult it with your doctor.

Spironolactone + Metolazone is used to provide relief from swelling and high blood pressure. It is not used to provide relief from bloating (swollen belly after eating food which might be caused by excessive gas production). If you are experiencing bloating caused by food then try to eat slowly, chew your food completely. Take fiber rich food also try to eat food in less quantity at a time. Taking probiotics or digestive enzyme supplements might be helpful in reducing bloating.

Ideally, the tablet has to be taken once or twice daily. It can be taken anytime but you are advised to take it in the morning because it causes more frequent urination which can disturb your sleep in the night. It can be taken with or without food but it is better to take it with food to avoid stomach upset.

Spironolactone + Metolazone is a prescription drug, hence do not take Spironolactone + Metolazone without consulting doctor. It can be harmful to patients to take this medicine without a doctor's advice.