Isolazine

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15 Tablet in 1 Strip
₹ 149 ₹157 4% OFF Save: ₹8
15 TABLET 1 Strip ₹ 149 ₹157 4% OFF Save: ₹8

  • Manufactured by:
  • Contains / Salt: Isosorbide Dinitrate (20 mg) + Hydralazine (37.5 mg)
  • Seller: Apollo Pharmacy Limited
    • This medicine is not available on Cash on Delivery(CoD)
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    Isolazine Information

    Isolazine, a prescription drug, is manufactured in various forms such as Tablet. The alternative uses of Isolazine have also been explained below.

    The optimal dosage of Isolazine is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

    Isolazine also has some side effects, the most common being Peripheral Edema, Jaw Pain, Chest Discomfort. Besides the aforementioned side effects, there are other adverse effects of Isolazine as well, which are listed below. Normally, these side effects of Isolazine are not long lasting and go away when the treatment is finished. However, if these continue for a longer time, consult your doctor right away.

    It is also important to note that Isolazine has a Moderate effect for pregnant women and Safe effect on lactating mothers. It is important to know if Isolazine has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Isolazine related warnings section.

    Isolazine can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Isolazine in conditions like Low Blood Pressure (Hypotension), Anemia, Angina. Other conditions have been mentioned below in the Isolazine contraindications section.

    Drug interactions for Isolazine have been reported in the medical literature. See below for a complete list.

    Along with the above-mentioned precautions, remember that taking Isolazine is considered not safe while driving, and is not addictive.



    Isolazine Benefits & Uses

    Isolazine is used to treat the following -

    Other Benefits

    Isolazine Dosage & How to Take

    This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

    Find the right dosage based on disease and age

    Age Group Dosage
    Adult
    • Disease: Heart Failure
    • Before or After Meal: Either
    • Single Maximum Dose: 1 Tablet
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 3 daily
    • Course Duration: As directed by the doctor
    • Special Instructions: strength 37.5 mg hydralazine and isosorbide dinitrate 20 mg
    Geriatric
    • Disease: Heart Failure
    • Before or After Meal: Either
    • Single Maximum Dose: 1 Tablet
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 3 daily
    • Course Duration: As directed by the doctor
    • Special Instructions: strength 37.5 mg hydralazine and isosorbide dinitrate 20 mg


    Isolazine Side Effects

    Based on research, the following side effects have been observed when Isolazine is used -

    Moderate

    • Decreased blood pressure
    • Palpitations (fluttering in chest)
    • Angina Pectoris

    Mild

    Common

    Isolazine Related Warnings

    • Is the use of Isolazine safe for pregnant women?


      Isolazine may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Isolazine again without your doctor's advice.

    • Is the use of Isolazine safe during breastfeeding?


      Breastfeeding women can safely use Isolazine.

    • What is the effect of Isolazine on the Kidneys?


      Isolazine rarely affects the kidneys.

    • What is the effect of Isolazine on the Liver?


      Isolazine may have mild side effects on the liver. Most people will never see any effect on the liver.

    • What is the effect of Isolazine on the Heart?


      Isolazine may have mild side effects on the heart. Most people will never see any effect on the heart.



    Severe Interaction of Isolazine with Other Drugs

    Isolazine should not be taken with following medicines due to severe side effects it may cause to patients -

    Severe

    SildenafilChlorpheniramine,Dextromethorphan,Paracetamol,Phenylephrine

      Moderate



      Isolazine Contraindications

      If you are suffering from any of the following diseases, you should not take Isolazine unless your doctor advises you to do so -



      Frequently asked Questions about Isolazine

      • Is this Isolazine habit forming or addictive?


        Isolazine is not addictive in nature.

      Isolazine Interactions with Food and Alcohol

      • Interaction between Food and Isolazine


        It is safe to take Isolazine with food.

      • Interaction between Alcohol and Isolazine


        No research has been done on this till date. Therefore, it is not known what the effect of taking Isolazine with alcohol will be.



      Frequently asked Questions about Isolazine

      Question over 4 years ago

      Does Isolazine lower blood pressure (hypotension)?

      Dr. Suhas Bhargav MBBS , General Physician

      Yes, Isolazine may lower blood pressure (hypotension) in some cases. It is an uncommon side effect of this drug. However, if you are experiencing lightheadedness or dizziness which is a symptom of low blood pressure (hypotension) then you are advised to lay down immediately till it subsides if it worsens then inform your doctor without further delay.

      Question about 5 years ago

      How to take Isolazine?

      Dr. Vedprakash Verma MBBS, MD , Cardiology

      Take Isolazine 2-3 times a day or as advised by your doctor. It has to be taken on an empty stomach because the presence of food might affect the absorption of this drug from the stomach. Precautions must be taken in patients with glaucoma, hypothyroidism, and improper liver or kidney function.

      Question about 5 years ago

      How does Isolazine work?

      Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

      Isolazine contains isosorbide dinitrate which is a vasodilator. It works by causing relaxation of vascular smooth muscle and dilation of the blood vessels (vasodilation) which promotes increase in oxygen and blood supply to the heart this also reduces the workload of the heart (reduces preload and afterload).

      Question almost 5 years ago

      Can I take paracetamol and Isolazine together?

      Dr. Uday Nath Sahoo MBBS , Internal Medicine

      Yes, you can take paracetamol and Isolazine together. No clinically significant drug interaction has been reported between them. However, if you feel any discomfort after taking this drug along with paracetamol then do not hesitate to inform your doctor.

      Question about 5 years ago

      Can I take Isolazine without consulting a doctor?

      Dr. Vedprakash Verma MBBS, MD , Cardiology

      No, Isolazine is a prescription drug, so do not take it without consulting a doctor. It can be harmful to the patient to take this medicine without a doctor's recommendation because it can cause very unpleasant side effects. Hence, the patient should seek doctors advice before taking this medication by himself or herself.



      See all substitutes for Isolazine


      This medicine data has been created by -

      Vikas Chauhan

      B.Pharma, Pharmacy
      5 Years of Experience


      References

      US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Isordil® Titradose™ (isosorbide dinitrate)

      KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 543-544

      April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 653-654

      US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hydralazine hydrochloride

      KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 566-567

      April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 651-653

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