Ascend

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Ascend Information

Ascend is a commercial drug that is prescribed in the form of Tablet. It is primarily used for the treatment of Acidity. Ascend also has some secondary and off-label uses. These are listed below.

The correct dosage of Ascend depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.

Ascend also has some side effects, the most common being Diarrhoea. Some other side effects of Ascend have been listed ahead. Normally, these side effects of Ascend are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.

It is also important to note that Ascend has a Safe effect for pregnant women and Moderate effect on lactating mothers. Warnings related to Ascend's effects on the liver, heart and kidney, if any, have been listed below.

Ascend is contraindicated in people with pre-existing medical conditions like Diarrhea (Loose Motions) as it can result in adverse effects. Other contraindications of Ascend have been discussed in the sections ahead.

Drug interactions for Ascend have been reported in the medical literature. See below for a complete list.

In addition to the above precautions for Ascend, it is important to know that it is not safe while driving, and is not habit-forming.



Ascend Benefits & Uses

Ascend is used to treat the following -

Main Benefits

Other Benefits

Ascend Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: GERD (Gastroesophageal Reflux Disease)
  • Before or After Meal: Before meal
  • Single Maximum Dose: 20 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 weeks
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: GERD (Gastroesophageal Reflux Disease)
  • Before or After Meal: Before meal
  • Single Maximum Dose: 20 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 weeks
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: GERD (Gastroesophageal Reflux Disease)
  • Before or After Meal: Before meal
  • Single Maximum Dose: 20 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 weeks
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: GERD (Gastroesophageal Reflux Disease)
  • Before or After Meal: Before meal
  • Single Maximum Dose: 10 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 8 weeks
  • Special Instructions: As prescribed by the doctor

Ascend Related Warnings

  • Is the use of Ascend safe for pregnant women?


    Pregnant women can take Ascend without worrying about any side effects.

    Safe
  • Is the use of Ascend safe during breastfeeding?


    Women who are breastfeeding can experience some moderate side effects of Ascend. Immediately discontinue Ascend if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

    Moderate
  • What is the effect of Ascend on the Kidneys?


    There are no side effects of Ascend on the kidneys.

    Safe
  • What is the effect of Ascend on the Liver?


    Ascend is rarely harmful for the liver.

    Mild
  • What is the effect of Ascend on the Heart?


    Ascend is completely safe for the heart.

    Safe


Severe Interaction of Ascend with Other Drugs

Ascend should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Ascend Contraindications

If you are suffering from any of the following diseases, you should not take Ascend unless your doctor advises you to do so -



Frequently asked Questions about Ascend

  • Is this Ascend habit forming or addictive?


    Ascend is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Ascend. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    There are no side effects of Ascend, so it is safe for use.

    Safe
  • Is it able to treat mental disorders?


    No, the use of Ascend in mental disorders is not effective.

    No

Ascend Interactions with Food and Alcohol

  • Interaction between Food and Ascend


    Taking Ascend with food is safe.

    Safe
  • Interaction between Alcohol and Ascend


    Consumption of alcohol and Ascend together may have severe effects on your health.

    Severe


Frequently asked Questions about Ascend

Question over 5 years ago

How to take Ascend?

Dr. Kumawat Vijay Kumar MBBS , General Physician

Ascend is available in tablet, capsule and injection form. It should be taken exactly as prescribed by your doctor. It can be taken with or without food because food does not affect the absorption of the drug. It should be taken the whole and swallowed with water. It should not be chewed, crushed or split. It should be taken at exactly the same time every day so that there is less chance of missing the dose. 

Question almost 5 years ago

Why Ascend is given along with vitamine B 12?

Dr. Sameer Awadhiya MBBS , Pediatrics

This is because a long-term use of Ascend can cause Vitamin B12 deficiency. Stomach acids help in the absorption of Vitamin B 12, and this drug suppresses stomach acid which is required for the absorption of vitamin B12. Hence patients taking [medicine] for a long time have Vitamin B12 deficiency. To replenish Vitamin B12 in your body your doctor prescribes this vitamin along with this medicine.

Question almost 5 years ago

Can Ascend cause allergy?

Dr. MBBS , General Physician, Other, Infectious Disease

Ascend may cause allergy in rare instances. An allergic reaction might lead to swelling of the face, development of a rash, throat tightness and difficulty in breathing. If you develop any of these symptoms, talk to your doctor immediately. He may stop Ascend for a while and examine you properly. 

Question about 5 years ago

Does Ascend lead to low magnesium levels?

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, Ascend might lead to low magnesium levels in persons who take it for at least 3 months. Magnesium helps in absorption of vitamin D and calcium, low level of magnesium will affect the absorption of Vit. D and calcium lead to decrease bone density and increases the risk of bone fracture. Low-level magnesium can be managed by taking a dietary supplement which is rich in magnesium. 

Question about 5 years ago

What is Ascend?

Dr. Yogesh Kumar MBBS , General Physician

Ascend is a brand name for rabeprazole. It belongs to a class of medications known as proton pump inhibitors. It is available in the form of a tablet, capsule, and injection. Ascend is used to alleviate the symptoms of gastroesophageal reflux disorder (GERD). GERD is a condition in which acid back-flows from the stomach to the esophagus (the tube which connects the stomach with throat) causing heartburn and injury to the esophagus. Ascend is used to prevent this damage. Ascend is also used to treat conditions like Zollinger Ellison syndrome (excessive acid is produced by the stomach). It is used for the treatment of ulcers (sores in the lining of stomach and intestine) and also used in combination with other antibiotics (such as amoxicillin and clarithromycin) to manage H.pylori infection.



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Aciphex® (rabeprazole sodium)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 653

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1077-1078

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