Defidin

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  • Manufactured by: Lupin Ltd
  • Contains / Salt: Amlodipine (5 mg)

Defidin Information

Defidin is a commercial drug that is prescribed in the form of Tablet. It is typically used for the treatment of High BP. Defidin also has some secondary and off-label uses. These are listed below.

The optimal dosage of Defidin is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. This information has been provided in detail in the dosage section.

While these are the most often observed Defidin side effects, there are can be others also. These have been listed below. Such side effects of Defidin normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Defidin is Severe for pregnant women and Unknown for women who are breastfeeding. Warnings related to Defidin's effects on the liver, heart and kidney, if any, have been listed below.

Defidin is contraindicated in people with pre-existing medical conditions like Low Blood Pressure (Hypotension), Coronary Artery Disease (CAD), Liver Disease as it can result in adverse effects. Some other conditions that can be affected by Defidin are listed in the contraindications section below.

Drug interactions for Defidin have been reported in the medical literature. A complete list of these interactions is given below.

In addition to these precautions, you may also note that Defidin is safe while driving, and is is addictive in nature.


Defidin Benefits & Uses

Defidin is used to treat the following -

Main Benefits

Other Benefits

Defidin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: High Blood Pressure
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage can be given up to 10 mg once daily
Geriatric
  • Disease: Chest Pain
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage can be given up to 10 mg once daily
13 - 18 years (Adolescent)
  • Disease: Chest Pain
  • Before or After Meal: After Meal
  • Single Maximum Dose: 2.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage can be given up to 5 mg once daily
2 - 12 years (Child)
  • Disease: High Blood Pressure
  • Before or After Meal: After Meal
  • Single Maximum Dose: 2.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage can be given up to 5 mg once daily

Defidin Related Warnings

  • Is the use of Defidin safe for pregnant women?


    Defidin shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Defidin safe during breastfeeding?


    In the absence of any scientific study about the side effects of Defidin in breastfeeding women, information on safety of Defidin is unavailable.

    Unknown
  • What is the effect of Defidin on the Kidneys?


    There can be some harmful effects on your kidneys after taking Defidin. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Defidin on the Liver?


    You may experience side effects on your liver after taking Defidin. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Defidin on the Heart?


    Using Defidin does not have any harmful effects on the heart.

    Safe

Severe Interaction of Defidin with Other Drugs

Defidin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Defidin Contraindications

If you are suffering from any of the following diseases, you should not take Defidin unless your doctor advises you to do so -


Frequently asked Questions about Defidin

  • Is this Defidin habit forming or addictive?


    Defidin is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, it is safe to do these activities or work after taking Defidin as it does not make you drowsy.

    Safe
  • Is it safe?


    Defidin should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Defidin in mental disorders is not effective.

    No

Defidin Interactions with Food and Alcohol

  • Interaction between Food and Defidin


    Due to a lack of research, nothing can be said about the consequences of taking Defidin together with food.

    Unknown
  • Interaction between Alcohol and Defidin


    Chances of side effects of drinking alcohol while taking Defidin are low. If you feel any adverse effects, please seek medical advice as soon as possible.

    Mild

Frequently asked Questions about Defidin

Question over 4 years ago

Can I take Defidin with telmisatan?

Dr. Gaurav MBBS , General Physician

Yes, Defidin can be taken with telmisartan. As per clinical studies, no harmful interaction has been reported after taking them. However, do not take it without doctors advise. A fixed-dose combination of Defidin and telmisartan is available in the market which is used for the treatment of hypertension (high blood pressure).

Question over 5 years ago

What is Defidin?

Dr. Vedprakash Verma MBBS, MD , Cardiology

Defidin is a brand name of amlodipine. It is a prescription drug that belongs to the class of medications called calcium channel blocker. It is available in solid oral dosage forms like tablet and capsule. It is used in the treatment of high blood pressure (high BP) and coronary artery disease. It is not recommended for heart failure. It is also used in the treatment of angina (chest pain).

Question about 5 years ago

Can I take Defidin without consulting a doctor?

Dr. Anand Singh MBBS , General Physician

Defidin is a prescription drug so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation.

Question about 5 years ago

Does Defidin cause edema?

Dr. Saikat Mukherjee MBBS , General Physician

Yes, Defidin can cause edema. It is the most common side effects of this drug. Usually swelling occurs in feet and ankle. If these effects cause troublesome, then consult your doctor regarding whether this effect arises due to amlodipine consumption or not. If yes, then you can stop taking this medicine with the help of doctor because of alternate treatment are also available. However, it is dose-related effects if taken a low dose, chances of edema are very less if consuming high dose the chances of edema are high.

Question almost 5 years ago

Is Defidin harmful for kidney?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

No, Defidin is not harmful to a kidney. However, it can cause some urinary problem such as urine retention and difficulty in passing urine. Do not hesitate to inform your doctor if you are facing any of the above while taking this drug.


See all substitutes for Defidin


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Norvasc® (amlodipine besylate)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 540, 549, 550

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 147-148

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