Disprin Plus

Yes, you can take Disprin Plus with aspirin. No drug-drug interaction has been reported between them. But you're recommended to consult your doctor before taking these two medications together.

Yes, you can take Disprin Plus with or without food, because it doesn't irritate the stomach lining, unlike other drugs. However, if you are taking NSAIDs (painkillers) such as Aspirin and Ibuprofen along with paracetamol it is best to take them with a light meal or a glass of milk.

Yes, Disprin Plus can be taken safely with a less sedative antihistaminic drug like cetirizine and loratadine etc. No harmful effects are reported. However, another group of antihistamine drug which causes drowsiness and sleepiness like chlorpheniramine, diphenhydramine etc. should not be taken together unless and until recommended by your doctor.

As we know Disprin Plus is most widely used 'over-the-counter' analgesic/antipyretic medicine. However, paracetamol overdose can cause serious adverse effects on the liver, it may be fatal. But fortunately, there is an antidote, N-acetylcysteine (NAC) given within 8 hours of Disprin Plus ingestion which usually can prevent all serious side effects of Disprin Plus poisoning. However, do not take NAC without consulting a doctor as your doctor will tell you the right way and methods to help you relieve from this drug poisoning.

You should take the minimum effective dose of Disprin Plus that reduces body pain and fever. It should be used for the shortest time period till you get relief. Take it as per doctor's advice do not exceed dosage. Ideally, 1 or 2 tablets (500 mg) every four to six hours can be safely taken, do not take more than four doses in 24 hours. Please note paracetamol 500 mg tablet should not be given to children below 10 years until and unless prescribed by a child specialist.