Dr. Kuldeep Meena MBBS, MD , Pulmonology

No harmful interactions have been reported between Dolo and codeine. Do not take it until and unless prescribed. However, if you are experiencing any unpleasant medicinal side effects such as nausea, stomach pain, and tremors after taking Dolo. Inform your doctor immediately.

ravi udawat MBBS , General Physician

As we know Dolo is most widely used 'over-the-counter' analgesic/antipyretic medicine. However, paracetamol overdose can cause serious adverse effects on the liver, it may be fatal. But fortunately, there is an antidote, N-acetylcysteine (NAC) given within 8 hours of Dolo ingestion which usually can prevent all serious side effects of Dolo poisoning. However, do not take NAC without consulting a doctor as your doctor will tell you the right way and methods to help you relieve from this drug poisoning.

Dr. Joydeep Sarkar MBBS , General Physician

You should take the minimum effective dose of Dolo that reduces body pain and fever. It should be used for the shortest time period till you get relief. Take it as per doctor's advice do not exceed dosage. Ideally, 1 or 2 tablets (500 mg) every four to six hours can be safely taken, do not take more than four doses in 24 hours. Please note paracetamol 500 mg tablet should not be given to children below 10 years until and unless prescribed by a child specialist.

Dr. Kishan Barnwal MBBS , General Physician

Yes, Dolo can be taken safely with a less sedative antihistaminic drug like cetirizine and loratadine etc. No harmful effects are reported. However, another group of antihistamine drug which causes drowsiness and sleepiness like chlorpheniramine, diphenhydramine etc. should not be taken together unless and until recommended by your doctor.

Dolo is being used by pregnant women for many years without any evident harmful effects on the baby. That's why it is usually recommended as the first-line painkiller for pregnant women. But it is not possible to say that this medicine is completely safe to use in pregnancy. You are highly recommended to check with your doctor/gynaecologist before taking any medicine even [medicine] during pregnancy.