Ivacaftor + Lumacaftor Benefits & Uses

Ivacaftor + Lumacaftor is used to treat the following -

Other Benefits

Cystic Fibrosis

Ivacaftor + Lumacaftor Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
13 - 18 years (Adolescent)	Disease: Cystic Fibrosis Before or After Meal: With meal Single Maximum Dose: 2 Tablet Dosage Form: Tablet Dosage Route: Oral Frequency: 12 hourly Course Duration: As directed by the doctor Special Instructions: strength 200 mg lumacaftor and 125 mg ivacaftor
2 - 12 years (Child)	Disease: Cystic Fibrosis Before or After Meal: With meal Single Maximum Dose: 2 Tablet Dosage Form: Tablet Dosage Route: Oral Frequency: 12 hourly Course Duration: As directed by the doctor Special Instructions: strength 100 mg lumacaftor and 125 mg ivacaftor, patients above 6 years old can take
Adult	Disease: Cystic Fibrosis Before or After Meal: With meal Single Maximum Dose: 2 Tablet Dosage Form: Tablet Dosage Route: Oral Frequency: 12 hourly Course Duration: As directed by the doctor Special Instructions: strength 200 mg lumacaftor and 125 mg ivacaftor
Geriatric	Disease: Cystic Fibrosis Before or After Meal: With meal Single Maximum Dose: 2 Tablet Dosage Form: Tablet Dosage Route: Oral Frequency: 12 hourly Course Duration: As directed by the doctor Special Instructions: strength 200 mg lumacaftor and 125 mg ivacaftor

Ivacaftor + Lumacaftor Side Effects

Based on research, the following side effects have been observed when Ivacaftor + Lumacaftor is used -

Moderate

Increased Liver Enzymes

Mild

Headache
Infection
Nasal congestion
Stomach ache (Read More - Home remedies for stomach pain)
Pharyngitis
Diarrhoea
Rash
Nausea or vomiting
Dizziness
Rhinitis
Muscle Ache (Read More - Home Remedies for Muscle Aches)
Acne
Joint pain
Cough

Common

Shortness of Breath

Ivacaftor + Lumacaftor Related Warnings

Is the use of Ivacaftor + Lumacaftor safe for pregnant women?

Pregnant women may get mild side effects from Ivacaftor + Lumacaftor.
Is the use of Ivacaftor + Lumacaftor safe during breastfeeding?

Women who are breastfeeding can experience some moderate side effects of Ivacaftor + Lumacaftor. Immediately discontinue Ivacaftor + Lumacaftor if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.
What is the effect of Ivacaftor + Lumacaftor on the Kidneys?

Ivacaftor + Lumacaftor rarely affects the kidneys.
What is the effect of Ivacaftor + Lumacaftor on the Liver?

Side effects of Ivacaftor + Lumacaftor rarely affect the liver.
What is the effect of Ivacaftor + Lumacaftor on the Heart?

Ivacaftor + Lumacaftor is completely safe for the heart.

Severe Interaction of Ivacaftor + Lumacaftor with Other Drugs

Ivacaftor + Lumacaftor should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Carbamazepine

Clarithromycin

Diltiazem

Fluconazole

Abemaciclib

Abemaciclib 150 Mg Tablet

Atazanavir

Carbamazepine

Diltiazem

Erythromycin

Ethinyl Estradiol,Levonorgestrel

Etonogestrel

Fluconazole

Moderate

Amprenavir

Amprenavir Capsule

Aprepitant

Ivacaftor + Lumacaftor Contraindications

If you are suffering from any of the following diseases, you should not take Ivacaftor + Lumacaftor unless your doctor advises you to do so -

Liver Disease
Kidney Disease
Cataract
Kidney Disease
Liver Disease
Hepatic Encephalopathy

Frequently asked Questions about Ivacaftor + Lumacaftor

Is this Ivacaftor + Lumacaftor habit forming or addictive?

No, you will not get addicted to Ivacaftor + Lumacaftor.

Ivacaftor + Lumacaftor Interactions with Food and Alcohol

Interaction between Food and Ivacaftor + Lumacaftor

Due to the absence of research, it is difficult to say how Ivacaftor + Lumacaftor and food will interact.
Interaction between Alcohol and Ivacaftor + Lumacaftor

Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Ivacaftor + Lumacaftor.