Mexate

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  • Manufactured by: Zydus Cadila
  • Contains / Salt: Methotrexate (15 mg)

Mexate Information

Mexate is an allopathic medicine Secondary and off-label uses of Mexate have also been mentioned below. The correct dosage of Mexate depends on the patient's age, gender, and medical history. This information has been provided in detail in the dosage section.


Mexate Benefits & Uses

Mexate is used to treat the following -

Other Benefits

Mexate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 6 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease:
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 60 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Mexate Side Effects

Based on research, the following side effects have been observed when Mexate is used -

Moderate

  • Stomatitis (Inflammation of the mouth)

Mild

  • Nausea or vomiting
  • Loss of appetite
  • Diarrhoea
  • Joint pain

Common

  • पेट दर्द

Mexate Related Warnings

  • Is the use of Mexate safe for pregnant women?


    Mexate should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Mexate safe during breastfeeding?


    Taking Mexate may lead to serious side effects if you are breastfeeding. Mexate should not be taken by breastfeeding women unless prescribed by the doctor.

    Severe
  • What is the effect of Mexate on the Kidneys?


    Mexate can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Mexate on the Liver?


    You may experience side effects on your liver after taking Mexate. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Mexate on the Heart?


    Mexate has very mild side effects on the heart.

    Mild

Severe Interaction of Mexate with Other Drugs

Mexate should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Mexate Contraindications

If you are suffering from any of the following diseases, you should not take Mexate unless your doctor advises you to do so -


Frequently asked Questions about Mexate

  • Is this Mexate habit forming or addictive?


    Forming a habit of Mexate has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Mexate does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

    Safe
  • Is it safe?


    Mexate is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Mexate is unable to treat or cure mental disorders.

    No

Mexate Interactions with Food and Alcohol

  • Interaction between Food and Mexate


    Due to a lack of research, nothing can be said about the consequences of taking Mexate together with food.

    Unknown
  • Interaction between Alcohol and Mexate


    Side effects of drinking alcohol and taking Mexate at the same time are rare and minor. However, if you face any side effects, talk to your doctor immediately.

    Mild

Frequently asked Questions about Mexate

Question almost 7 years ago

Can Mexate cause nausea and vomiting?

Dr. Bharat MBBS , General Physician

Yes, Mexate causes nausea and vomiting. It is a known side effect of this drug. For relief from nausea and vomiting try to take lime water, avoid eating spicy food even after that it persists or becomes severe then discuss it with your doctor.

Question almost 7 years ago

Is Mexate safe to use?

Dr. , General Physician

Yes, Mexate is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as gingivitis (inflammation of gum), mouth ulcers, and diarrhoea. If you experience above-mentioned side effects after taking this medicine then inform your doctor and follow his/her instructions.

Question over 6 years ago

Can Mexate cause hair loss?

Dr. Suhas Bhargav MBBS , General Physician

Yes, Mexate causes hair loss (alopecia). It is a known side effect of this drug. This side effect is reversible in nature and it is resolved after the discontinuation of this drug.

Question over 6 years ago

Can Mexate cure psoriasis?

Dr. Sameer Awadhiya MBBS , Pediatrics

Mexate can help in curing psoriasis which is caused by the overactive immune system. It is used in the treatment of severe cases of psoriasis when another treatment with other medications is not working. Mexate contains methotrexate that suppresses the body's overactive immune system. This helps in reducing the severity of psoriasis so that patient can use milder therapy for relief. 

Question about 7 years ago

How long can I safely take Mexate?

Dr. Manju Shekhawat MBBS , General Physician

Take Mexate as directed by your doctor. Do not take this medicine longer than prescribed to avoid unpleasant side effects.


See all substitutes for Mexate


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methotrexate

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862-863

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 832-834


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