Neotrexate Injection

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1 Injection in 1 Packet
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1 INJECTION 1 Packet ₹ 50.7
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Neotrexate Injection Information

Neotrexate Injection is a prescription drug, available for use as Injection. It is typically used for the treatment of Non-Hodgkin Lymphoma, Lymphoma. Other than this, Neotrexate Injection has some other therapeutic uses, which have been discussed ahead.

The correct dosage of Neotrexate Injection depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

Neotrexate Injection also has some side effects, the most common being Abdominal Pain. Besides the aforementioned side effects, there are other adverse effects of Neotrexate Injection as well, which are listed below. Usually, these side effects of Neotrexate Injection go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

In addition, Neotrexate Injection's effect is Severe during pregnancy and Severe for lactating mothers. It is important to know if Neotrexate Injection has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Neotrexate Injection related warnings section.

Neotrexate Injection can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Neotrexate Injection in conditions like Infections, Liver Disease, Anemia. Some other conditions that can be affected by Neotrexate Injection are listed in the contraindications section below.

Drug reaction of Neotrexate Injection with other medicines has been reported. See below for a complete list.

In addition to the above precautions for Neotrexate Injection, it is important to know that it is safe while driving, and is habit-forming.



Neotrexate Injection Benefits & Uses

Neotrexate Injection is used to treat the following -

Other Benefits

Neotrexate Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 6 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 60 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Neotrexate Injection Related Warnings

  • Is the use of Neotrexate Injection safe for pregnant women?


    Neotrexate can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Neotrexate Injection safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Neotrexate. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Neotrexate Injection on the Kidneys?


    Kidney can be affected by Neotrexate. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.

    Moderate
  • What is the effect of Neotrexate Injection on the Liver?


    The liver can be affected by Neotrexate. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Neotrexate only after medical advice.

    Moderate
  • What is the effect of Neotrexate Injection on the Heart?


    Neotrexate may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Neotrexate Injection Contraindications

If you are suffering from any of the following diseases, you should not take Neotrexate Injection unless your doctor advises you to do so -



Frequently asked Questions about Neotrexate Injection

  • Is this Neotrexate Injection habit forming or addictive?


    No, you will not get addicted to Neotrexate Injection.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Neotrexate Injection does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

    Safe
  • Is it safe?


    Yes, but take Neotrexate Injection only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Neotrexate Injection cannot treat any kind of mental disorder.

    No

Neotrexate Injection Interactions with Food and Alcohol

  • Interaction between Food and Neotrexate Injection


    Due to the absence of research, it is difficult to say how Neotrexate Injection and food will interact.

    Unknown
  • Interaction between Alcohol and Neotrexate Injection


    Taking [medicine] and alcohol at the same time may lead to mild side effects. Contact your doctor right away if you observe any side effects.

    Mild


Frequently asked Questions about Neotrexate Injection

Question over 5 years ago

What is Neotrexate?

Dr. R.K Singh MBBS , Diabetology

Neotrexate is a brand name of methotrexate and it comes in the form of tablet and injection. It is a chemotherapy drug that belongs to the class of drug known as antimetabolites and it also has immunosuppressant properties. It is a prescription drug which is used for the treatment of various types of cancers such as breast cancer, bone cancer, head, and neck cancer. It is also used in the treatment of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease.

Question over 4 years ago

Does Neotrexate cause cancer?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Neotrexate contains methotrexate (a chemotherapy) which is used in the treatment of various types of cancers. Nonetheless, it has been associated with an increased risk for melanoma, non-Hodgkin's lymphoma, and lung cancer.

Question about 5 years ago

Is Neotrexate safe to use?

Dr. , General Physician

Yes, Neotrexate is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as gingivitis (inflammation of gum), mouth ulcers, and diarrhoea. If you experience above-mentioned side effects after taking this medicine then inform your doctor and follow his/her instructions.

Question over 4 years ago

Does Neotrexate raise blood sugar?

Dr. Abhijit MBBS , General Physician

No, Neotrexate does not raise blood sugar levels (hyperglycemia). It has not been reported by the patients who are taking it. However, if you are experiencing increased thirst, trouble concentrating, and frequent urination which are symptoms of increased blood sugar levels (hyperglycemia) then do discuss with your doctor.

Question about 5 years ago

How to take Neotrexate?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

The dosage of this drug may vary depending on the diagnosis and the patient's medical condition. Take Neotrexate as advised by your doctor. Ideally, oral Neotrexate has to be taken empty stomach because the presence of food might affect the absorption of this drug from the stomach. Precautions must be taken in patients with bone marrow depression, and improper liver or kidney function.



See all substitutes for Neotrexate



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methotrexate

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862-863

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 832-834



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