ravi udawat MBBS , General Physician

As we know Paracetamol + Oxycodone is most widely used 'over-the-counter' analgesic/antipyretic medicine. However, paracetamol overdose can cause serious adverse effects on the liver, it may be fatal. But fortunately, there is an antidote, N-acetylcysteine (NAC) given within 8 hours of Paracetamol + Oxycodone ingestion which usually can prevent all serious side effects of Paracetamol + Oxycodone poisoning. However, do not take NAC without consulting a doctor as your doctor will tell you the right way and methods to help you relieve from this drug poisoning.

Dr. Kapil Sharma MBBS , General Physician

Yes, you can take Paracetamol + Oxycodone with aspirin. No drug-drug interaction has been reported between them. But you're recommended to consult your doctor before taking these two medications together.

Dr. Saurabh Shakya MBBS , General Physician

Yes, you can use Paracetamol + Oxycodone in a migraine. Paracetamol and other NSAIDs are used in treating migraine. However, there are other medicines available that are better for treating migraine than Paracetamol + Oxycodone. Please consult a doctor to know about these alternative medicines.

ravi udawat MBBS , General Physician

An overdose occurs when more than the required amount (toxic levels) of [medicine] is taken. Initial symptoms of Paracetamol + Oxycodone overdose includes loss of appetite, drowsiness, seizures, abdominal pain, nausea, and vomiting. Later progressive symptoms may include pain in your upper stomach, dark colored urine, yellowing of your skin or the white patches in your eyes, liver damage and in rare cases, it can also lead to coma. So, by any chance, if you have accidentally taken more than the required dose of Paracetamol + Oxycodone inform your doctor immediately.

Dr. Joydeep Sarkar MBBS , General Physician

You should take the minimum effective dose of Paracetamol + Oxycodone that reduces body pain and fever. It should be used for the shortest time period till you get relief. Take it as per doctor's advice do not exceed dosage. Ideally, 1 or 2 tablets (500 mg) every four to six hours can be safely taken, do not take more than four doses in 24 hours. Please note paracetamol 500 mg tablet should not be given to children below 10 years until and unless prescribed by a child specialist.