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Safedol is a commercial drug that is prescribed in the form of Capsule. Other than this, Safedol has some other therapeutic uses, which have been discussed ahead.
The optimal dosage of Safedol is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.
The side effects typically associated with Safedol include Diarrhoea. Apart from the aforementioned side effects, Safedol can also lead to other problems, which have been listed below. Usually, these side effects of Safedol go away soon, and do not persist beyond the duration of the treatment. However, if these continue for a longer time, consult your doctor right away.
In addition, Safedol's effect is Severe during pregnancy and Mild for lactating mothers. In addition, Safedol's effects on the liver, heart and kidney are discussed below in the Safedol related warnings section.
Individuals suffering from medical conditions like Diarrhea (Loose Motions), Stomach Infection, Skin Rash must refrain from the use of Safedol since this can cause severe adverse effects. Other conditions have been mentioned below in the Safedol contraindications section.
Drug reaction of Safedol with other medicines has been reported. A complete list of these interactions is given below.
In addition to these precautions, you may also note that Safedol is safe while driving, and is is addictive in nature.
Safedol is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
Based on research, the following side effects have been observed when Safedol is used -
Severe
Moderate
Mild
Common
Is the use of Safedol safe for pregnant women?
Safedol can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Safedol safe during breastfeeding?
Breastfeeding women can take Safedol as it bears very minor side effects for them.
What is the effect of Safedol on the Kidneys?
There may be some severe side effects of Safedol on your kidney. Do not take it unless a doctor says so.
What is the effect of Safedol on the Liver?
There may be severe side effects of Safedol on your liver. Do not take it unless a doctor says so.
What is the effect of Safedol on the Heart?
The heart can be affected by Safedol. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.
Safedol should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Safedol unless your doctor advises you to do so -
Is this Safedol habit forming or addictive?
No, there is no any evidence that Safedol is addictive.
Interaction between Food and Safedol
There is no information on the effects of taking Safedol with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Safedol
Consult your doctor before consuming alcohol while taking Safedol as it can have severe side effects.
Yes, Safedol might lead to low magnesium levels in persons who take it for at least 3 months. Magnesium helps in absorption of vitamin D and calcium, low level of magnesium will affect the absorption of Vit. D and calcium lead to decrease bone density and increases the risk of bone fracture. Low-level magnesium can be managed by taking a dietary supplement which is rich in magnesium.
Yes, Safedol is given in combination with domperidone. A fixed-dose combination of [Medicinie] and domperidone is available in the market which is used in the treatment of GERD and other stomach related problems.
Yes, Safedol is given in combination with itopride. The combination is used for the management of gastro-esophageal reflux disorder (GERD).
Safedol is a brand name for rabeprazole. It belongs to a class of medications known as proton pump inhibitors. It is available in the form of a tablet, capsule, and injection. Safedol is used to alleviate the symptoms of gastroesophageal reflux disorder (GERD). GERD is a condition in which acid back-flows from the stomach to the esophagus (the tube which connects the stomach with throat) causing heartburn and injury to the esophagus. Safedol is used to prevent this damage. Safedol is also used to treat conditions like Zollinger Ellison syndrome (excessive acid is produced by the stomach). It is used for the treatment of ulcers (sores in the lining of stomach and intestine) and also used in combination with other antibiotics (such as amoxicillin and clarithromycin) to manage H.pylori infection.
Rarely, Safedol causes hair loss. This is a reversible side effect of Safedol, the problem goes away after discontinuation of this drug. For partial hair loss, you are advised to use hair tonic and discuss with your doctor about a better treatment option for hair loss.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Aciphex® (rabeprazole sodium)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 653
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1077-1078
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 427-429
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 204
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Voltaren® (diclofenac sodium)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Diclofenac (diclofenac sodium)
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Solaraze® (diclofenac sodium)
