Xplocef

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1 Injection in 1 Packet Out of Stock
₹ 717
1 INJECTION 1 Packet ₹ 717
  • Cannot be Sold Online

  • Manufactured by:
  • Contains / Salt: Ceftriaxone (2000 mg) + Vancomycin (1000 mg)
  • Free Shipping Available
     

Xplocef Information

Xplocef is a prescription drug, available for use as Injection. Xplocef also has some secondary and off-label uses. These are listed below.

The correct dosage of Xplocef depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. This information has been provided in detail in the dosage section.

While these are the most often observed Xplocef side effects, there are can be others also. These have been listed below. Usually, these side effects of Xplocef go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

In addition, Xplocef's effect is Severe during pregnancy and Safe for lactating mothers. Further, the section on Xplocef related warnings talks about Xplocef's effects on the liver, heart and kidney.

Xplocef is contraindicated in people with pre-existing medical conditions like Jaundice, Drug Allergy, Kidney Disease as it can result in adverse effects. Other contraindications of Xplocef have been discussed in the sections ahead.

Drug reaction of Xplocef with other medicines has been reported. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Xplocef is considered safe while driving, and is addictive.



Xplocef Benefits & Uses

Xplocef is used to treat the following -

Other Benefits

Xplocef Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Endocarditis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 3 g
  • Dosage Route: Parenteral
  • Frequency: 2 daily
  • Course Duration: 6 weeks
  • Special Instructions: strength 1 g vancomycin and 2 g ceftriaxone
Geriatric
  • Disease: Endocarditis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 3 g
  • Dosage Route: Parenteral
  • Frequency: 2 daily
  • Course Duration: 6 weeks
  • Special Instructions: strength 1 g vancomycin and 2 g ceftriaxone


Xplocef Side Effects

Based on research, the following side effects have been observed when Xplocef is used -

Severe

Moderate

  • Peripheral Edema
  • Decreased white blood cell count (neutrophils)

Mild

Xplocef Related Warnings

  • Is the use of Xplocef safe for pregnant women?


    Pregnant women may get severe side effects after taking Xplocef. If you are pregnant, do not take Xplocef without a doctor's advice.

  • Is the use of Xplocef safe during breastfeeding?


    Breastfeeding women can safely use Xplocef.

  • What is the effect of Xplocef on the Kidneys?


    Very few cases of side effects of Xplocef on kidney have been reported.

  • What is the effect of Xplocef on the Liver?


    Xplocef does not damage the liver.

  • What is the effect of Xplocef on the Heart?


    You can take Xplocef without any fear of damage to the heart.



Severe Interaction of Xplocef with Other Drugs

Xplocef should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Xplocef Contraindications

If you are suffering from any of the following diseases, you should not take Xplocef unless your doctor advises you to do so -



Frequently asked Questions about Xplocef

  • Is this Xplocef habit forming or addictive?


    Forming a habit of Xplocef has not been reported.

Xplocef Interactions with Food and Alcohol

  • Interaction between Food and Xplocef


    You can take Xplocef with food.

  • Interaction between Alcohol and Xplocef


    It is difficult to say anything about the effect of Xplocef and alcohol. No research has been done on this yet.



Frequently asked Questions about Xplocef

Question over 4 years ago

Does Xplocef cause liver toxicity?

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Xplocef can cause liver toxicity if taken in higher doses for a long time. You are advised to get regular liver function tests done to keep a check on proper liver functioning while taking this drug.

Question about 5 years ago

How to take Xplocef?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Do not self-administer Xplocef. It comes in the form of injection and preferably taken 1 - 2 times in a day (Intravenously or Intramuscularly). Take this medicine in the required quantity and duration as prescribed by your doctor. Discontinuing the a in between may promote resistant bacteria which result in a relapse of the infection. You are recommended to complete the 7 - 14 days course even after getting symptomatic relief. In case you feel any discomfort such as breathing difficulties and skin reactions while taking this medicine please inform your doctor immediately. 

Question almost 5 years ago

Can Xplocef cause hemolytic anemia?

Dr. Sameer Awadhiya MBBS , Pediatrics

Occasionally Xplocef can cause a drug to induce hemolytic anemia (abnormal Red blood cell breakdown). However, if your blood reports are showing abnormal hemolytic anemia after taking this drug please discuss with your doctor.

Question about 5 years ago

How does Xplocef work?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Xplocef works by inhibiting the growth of the bacterial cell wall which is essential for the growth of bacteria. Hence, in this way, it prevents us from bacterial infection.

Question almost 5 years ago

Can Xplocef cause thrombocytopenia?

Dr. Kishan Barnwal MBBS , General Physician

Occasionally Xplocef can cause drug-induced thrombocytopenia (blood clot formation in a vessel). However, if you experience severe thrombocytopenia after taking this medicine, please immediately seek medical help. 



See all substitutes for Xplocef


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ceftriaxone

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 727-728

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 307-311

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Vancomycin Hydrochloride

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 757

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1246-1248

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