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Ofloxacin is a prescription drug, available for use as Injection. Urinary Tract Infection, Ear Infection, Bacterial Infections are some of its major therapeutic uses. Secondary and off-label uses of Ofloxacin have also been mentioned below.
The right dosage of Ofloxacin depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.
While these are the most often observed Ofloxacin side effects, there are can be others also. These have been listed below. Normally, these side effects of Ofloxacin are not long lasting and go away when the treatment is finished. However, if these continue for a longer time, consult your doctor right away.
It is also important to note that Ofloxacin has a Moderate effect for pregnant women and Moderate effect on lactating mothers. Warnings related to Ofloxacin's effects on the liver, heart and kidney, if any, have been listed below.
Ofloxacin is contraindicated in people with pre-existing medical conditions like Atrial Fibrillation, Heart Failure, Myasthenia Gravis (MG) as it can result in adverse effects. The section on Ofloxacin contraindications lists all such conditions.
Drug interactions for Ofloxacin have been reported in the medical literature. A complete list of these interactions is given below.
You should also be aware that Ofloxacin is not safe while driving, and is not addiction.
Ofloxacin is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
Based on research, the following side effects have been observed when Ofloxacin is used -
Severe
Moderate
Mild
Is the use of Ofloxacin safe for pregnant women?
Ofloxacin may have some side effects during pregnancy. Pregnant women should discontinue the use of Ofloxacin, and talk to their doctor, if they notice any discomfort.
Is the use of Ofloxacin safe during breastfeeding?
Breastfeeding women may feel side effects of Ofloxacin. If you see any side effects, stop taking Ofloxacin immediately and talk to your doctor. Take Ofloxacin again, only after your doctor's advice.
What is the effect of Ofloxacin on the Kidneys?
Ofloxacin rarely affects the kidneys.
What is the effect of Ofloxacin on the Liver?
Ofloxacin is rarely harmful for the liver.
What is the effect of Ofloxacin on the Heart?
Ofloxacin has very mild side effects on the heart.
Ofloxacin should not be taken with following medicines due to severe side effects it may cause to patients -
Life Threatening
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Ofloxacin unless your doctor advises you to do so -
Is this Ofloxacin habit forming or addictive?
Forming a habit of Ofloxacin has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
After taking Ofloxacin you may feel sleepy. So it is not advised to perform these activities.
Is it safe?
Yes, but take Ofloxacin only as per medical advice.
Is it able to treat mental disorders?
No, the use of Ofloxacin in mental disorders is not effective.
Interaction between Food and Ofloxacin
Some foods when eaten with Ofloxacin can alter the onset of actions. Discuss this with your doctor.
Interaction between Alcohol and Ofloxacin
Consuming Ofloxacin with alcohol can have many serious effects on your body.
Ofloxacin is a broad-spectrum antibiotic, active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the bacterial cell division and stops the working of enzyme which is responsible for cell division. It is effective against a large number of bacteria, even those bacteria which are resistant to other drugs.
Yes, Ofloxacin is safe to use, if taken in the prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as stomach pain, nausea, diarrhea, headache, difficulty in breathing, and constipation.
Ofloxacin can be taken with doxycycline. No drug-drug interactions are reported between them. Doxycyclin also does not affect the absorption of this drug. However, it doesn't mean that no interaction could exist. Please consult your doctor, if you feel any complication after consuming these two medicines at the same time.
Yes, you can take Ofloxacin for UTI infection. It is the first-line drug for treating UTI infection. It is active against the bacteria which causes UTI infection. However, you must follow the entire course of this medicine and do not discontinue medication without consulting your doctor.
Ofloxacin is not recommended as the first-line of drug for treating sinus infection. However, if there are no other alternatives available then you can take it, after doctor's advice.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1400
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 713
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Floxin® (ofloxacin)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ocuflox® (ofloxacin)