Amikamac

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Amikamac Information

Amikamac is a prescription medicine that is available as a Injection. Urinary Tract Infection are some of its major therapeutic uses. Amikamac also has some secondary and off-label uses. These are listed below.

The optimal dosage of Amikamac is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

Apart from the aforementioned side effects, Amikamac can also lead to other problems, which have been listed below. Usually, these side effects of Amikamac go away soon, and do not persist beyond the duration of the treatment. However, if these continue for a longer time, consult your doctor right away.

In addition, Amikamac's effect is Severe during pregnancy and Unknown for lactating mothers. It is important to know if Amikamac has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Amikamac related warnings section.

Individuals suffering from medical conditions like Dehydration, Parkinson's Disease, Hearing Loss must refrain from the use of Amikamac since this can cause severe adverse effects. Other conditions have been mentioned below in the Amikamac contraindications section.

Additionally, Amikamac may also adversely react with other medicines. See below for a complete list.

In addition to these precautions, you may also note that Amikamac is safe while driving, and is is addictive in nature.



Amikamac Benefits & Uses

Amikamac is used to treat the following -

Main Benefits

Other Benefits

Amikamac Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Bacterial Infections
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Urinary Tract Infection (UTI)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor

Amikamac Related Warnings

  • Is the use of Amikamac safe for pregnant women?


    Pregnant women may get severe side effects after taking Amikamac. If you are pregnant, do not take Amikamac without a doctor's advice.

    Severe
  • Is the use of Amikamac safe during breastfeeding?


    No research work has been carried out till date on effect of Amikamac on breastfeeding women. So it is not known whether taking Amikamac will cause side effects or not.

    Unknown
  • What is the effect of Amikamac on the Kidneys?


    Effects of Amikamac on kidney can be severe. It is not safe to use it without doctor's advice.

    Severe
  • What is the effect of Amikamac on the Liver?


    Amikamac is rarely harmful for the liver.

    Mild
  • What is the effect of Amikamac on the Heart?


    Amikamac has very mild side effects on the heart.

    Mild


Severe Interaction of Amikamac with Other Drugs

Amikamac should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Amikamac Contraindications

If you are suffering from any of the following diseases, you should not take Amikamac unless your doctor advises you to do so -



Frequently asked Questions about Amikamac

  • Is this Amikamac habit forming or addictive?


    Amikamac does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Amikamac since it does not cause drowsiness.

    Safe
  • Is it safe?


    Yes, but consume Amikamac only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Amikamac for mental disorders.

    No

Amikamac Interactions with Food and Alcohol

  • Interaction between Food and Amikamac


    Taking Amikamac with food does not harm your health.

    Safe
  • Interaction between Alcohol and Amikamac


    It is difficult to say anything about the effect of Amikamac and alcohol. No research has been done on this yet.

    Unknown


Frequently asked Questions about Amikamac

Question almost 5 years ago

Can I take Amikamac with penicillin?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Amikamac cannot be taken with penicillin. Because penicillin inactivates the Amikamac by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Amikamac should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function. 

Question about 5 years ago

How to take Amikamac?

Dr. Abhijit MBBS , General Physician

Do not self-administer Amikamac. It comes in the form of injection and given preferably 2 - 3 times in a day (Intravenously). Discontinuing the medicine in between may promote resistant bacteria which result in a relapse of the infection. You are recommended to complete the 7 - 10 days course even after getting symptomatic relief. In case you feel any discomfort such as hearing loss and nephrotoxicity while taking Amikamac please inform your doctor immediately. 

Question over 5 years ago

What is Amikamac?

Amikamac is a brand name for amikacin. It is a prescription drug which belongs to the class of medication known as an aminoglycoside antibiotic. It is a broad spectrum antibiotic which is used for the treatment of bacterial infection such as bone, joint, skin, intra-abdominal, pneumonia, and respiratory tract infection. It is used for short-term treatment (7 - 10 days) of bacterial infection in different part of the body. It is also used for the treatment of neonatal sepsis when sensitivity testing indicates that other aminoglycosides cannot be used.

Question about 5 years ago

Can I take Amikamac without consulting a doctor?

Dr. Abhijit MBBS , General Physician

Amikamac is a prescription drug, hence do not take Amikamac without consulting doctor. It can be harmful to patients to take this medicine without a doctor's advice.

Question about 5 years ago

Can I discontinue Amikamac on my own without doctors advice?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

Discontinuing Amikamac on your own can increase the chances of bacterial resistance and infection relapse. It is recommended that you always consult your doctor if you have decided to discontinue this medicine.



See all substitutes for Amikamac


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137

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