Brukin

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1 Injection in 1 Packet Out of Stock
₹ 60
1 INJECTION 1 Packet ₹ 60
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  • Contains / Salt: Amikacin (500 mg)
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Brukin Information

Brukin is a prescription medicine that is available as a Injection. It is typically used for the treatment of Urinary Tract Infection. Secondary and off-label uses of Brukin have also been mentioned below.

The right dosage of Brukin depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.

Some other side effects of Brukin have been listed ahead. Normally, these side effects of Brukin are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.

In addition, Brukin's effect is Severe during pregnancy and Unknown for lactating mothers. In addition, Brukin's effects on the liver, heart and kidney are discussed below in the Brukin related warnings section.

Brukin is not recommended if you suffer from certain medical conditions as it can have adverse effects. Dehydration, Parkinson's Disease, Hearing Loss are examples of such conditions. Some other conditions that can be affected by Brukin are listed in the contraindications section below.

Besides this, Brukin may also have severe interaction with some medicines. See below for a complete list.

You should also be aware that Brukin is safe while driving, and is addiction.



Brukin Benefits & Uses

Brukin is used to treat the following -

Main Benefits

Other Benefits

Brukin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Bacterial Infections
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Urinary Tract Infection (UTI)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor


Brukin Side Effects

Based on research, the following side effects have been observed when Brukin is used -

Moderate

Mild

Unknown

  • Uncoordinated Body Movements
  • Hearing Loss
  • Renal Impairment
  • Seizures (uncontrollable jerking of limbs)

Brukin Related Warnings

  • Is the use of Brukin safe for pregnant women?


    Brukin has many dangerous side effects in pregnant women. If you are pregnant, do not consume Brukin without medical advice.

    Severe
  • Is the use of Brukin safe during breastfeeding?


    There is no research available on the side effects of Brukin in breastfeeding women. Therefore, its impact is unknown.

    Unknown
  • What is the effect of Brukin on the Kidneys?


    Consumption of Brukin can harm the kidneys. So it is important to take medical advice beforehand.

    Severe
  • What is the effect of Brukin on the Liver?


    Very few cases of side effects of Brukin on the liver have been reported.

    Mild
  • What is the effect of Brukin on the Heart?


    Side effects of Brukin rarely affect the heart.

    Mild


Severe Interaction of Brukin with Other Drugs

Brukin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Brukin Contraindications

If you are suffering from any of the following diseases, you should not take Brukin unless your doctor advises you to do so -



Frequently asked Questions about Brukin

  • Is this Brukin habit forming or addictive?


    Brukin is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Brukin will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

    Safe
  • Is it safe?


    Yes, but consume Brukin only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Brukin cannot treat any kind of mental disorder.

    No

Brukin Interactions with Food and Alcohol

  • Interaction between Food and Brukin


    Taking Brukin with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Brukin


    Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Brukin.

    Unknown


Frequently asked Questions about Brukin

Question over 4 years ago

Is Brukin ototoxic?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Yes, Brukin has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.

Question over 4 years ago

Is Brukin nephrotoxic?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, Brukin is nephrotoxic. Nephrotoxicity depends on dose and duration of therapy. Thus, nephrotoxicity is likely to occur if Brukin taken a high dose for a long time or may occur if the drug is given to a patient that already suffer from kidney problem. Nephrotoxicity associated with this drug may reduce or minimize by taking some precaution before consuming this drug like monitor kidney functions regularly and do not take it in high doses. Avoid taking Brukin with another nephrotoxic drug. If you notice any urine discoloration after taking this drug then inform your doctor immediately.

Question over 4 years ago

Does Brukin cover pseudomonas?

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, Brukin is effective against bacteria (Pseudomonas). But it is also found that Pseudomonas can get resistant to this drug and in that case Brukin will not produce desired results. If you are experiencing no symptomatic relief after taking this medicine then inform your doctor and follow his/her instructions.

Question about 5 years ago

How does Brukin work?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Brukin is a broad-spectrum antibiotic which is active against both Gram-positive and Gram-negative bacteria. It works by preventing the synthesis of proteins that bacteria need to survive, in the absence of protein synthesis bacteria become vulnerable and dies. It is effective against different types of bacteria such as Escherichia coli, Proteus species, S. aureus, Acinetobacter and Serratia species.

Question almost 5 years ago

Can I take Brukin with penicillin?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Brukin cannot be taken with penicillin. Because penicillin inactivates the Brukin by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Brukin should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function. 



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137

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