Flucole

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  • Manufactured by: Kim Lab
  • Contains / Salt: Fluconazole (150 mg)
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Flucole Information

Flucole is a commercial drug that is prescribed in the form of Tablet. Fungal Infections, Candidal Infection, Urinary Tract Infection are some of its major therapeutic uses. Other than this, Flucole has some other therapeutic uses, which have been discussed ahead.

The right dosage of Flucole depends on the age, gender, and medical history of the patient. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

While these are the most often observed Flucole side effects, there are can be others also. These have been listed below. These side effects of Flucole are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Flucole is Severe for pregnant women and Safe for women who are breastfeeding. Warnings related to Flucole's effects on the liver, heart and kidney, if any, have been listed below.

Flucole is contraindicated in people with pre-existing medical conditions like Liver Disease as it can result in adverse effects. Some other conditions that can be affected by Flucole are listed in the contraindications section below.

Drug interactions for Flucole have been reported in the medical literature. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Flucole is considered not safe while driving, and is not addictive.



Flucole Benefits & Uses

Flucole is used to treat the following -

Other Benefits

Flucole Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult(Female)
  • Disease: Vaginal Yeast Infection
  • Before or After Meal: After Meal
  • Single Maximum Dose: 150 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 3 days
  • Special Instructions: Then once a week for 6 months
Adult
  • Disease: Fungal Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 400 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 1 days
  • Special Instructions: Then 200 - 800 mg/day for 28 days
Geriatric
  • Disease: Fungal Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 400 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 1 days
  • Special Instructions: Then 200 - 800 mg/day for 28 days
13 - 18 years (Adolescent)
  • Disease: Fungal Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 12 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 weeks
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Fungal Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 6 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 weeks
  • Special Instructions: As prescribed by the doctor

Flucole Related Warnings

  • Is the use of Flucole safe for pregnant women?


    Flucole should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Flucole safe during breastfeeding?


    Breastfeeding women can safely use Flucole.

    Safe
  • What is the effect of Flucole on the Kidneys?


    Flucole can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Flucole on the Liver?


    Flucole has very mild side effects on the liver.

    Mild
  • What is the effect of Flucole on the Heart?


    Flucole may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Flucole with Other Drugs

Flucole should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Flucole Contraindications

If you are suffering from any of the following diseases, you should not take Flucole unless your doctor advises you to do so -



Frequently asked Questions about Flucole

  • Is this Flucole habit forming or addictive?


    Forming a habit of Flucole has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Flucole as you may feel sleepy.

    Dangerous
  • Is it safe?


    Flucole is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Flucole is unable to treat or cure mental disorders.

    No

Flucole Interactions with Food and Alcohol

  • Interaction between Food and Flucole


    Taking Flucole with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Flucole


    No research has been done on this till date. Therefore, it is not known what the effect of taking Flucole with alcohol will be.

    Unknown


Frequently asked Questions about Flucole

Question about 5 years ago

Does Flucole cause stomach upset?

Dr. Abhijit MBBS , General Physician

Rarely, Flucole can cause stomach upset especially when it is intravenously administered (route injectible). On the contrary, oral administration of Flucole has been reported to cause stomach upset such as indigestion, stomach pain, diarrhea, and nausea. Keep your doctor informed in case you are experiencing stomach disturbances while taking this drug.

Question over 5 years ago

How does Flucole work?

Dr. Manoj Meena MBBS , General Physician

Flucole inhibit the fungal cytochrome P450 enzyme lanosterol 14- demethylase and thus block ergosterol synthesis leading to membrane abnormalities in the fungus. It kills the fungus by destroying its cell membrane.

Question almost 5 years ago

Is Flucole nephrotoxic?

Dr. R.K Singh MBBS , Diabetology

No, Usually Flucole does not cause nephrotoxicity. But as per FDA reports patients above 65 years have exhibited acute renal failure hence elderly patients should take Flucole only when prescribed. However, the exact mechanism of renal failure associated with this drug is not yet known.

Question over 4 years ago

Can Flucole cause irregular period?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Rarely, Flucole can cause irregular periods. However, if you're experiencing conditions such as leucorrhoea (whitish or yellowish vaginal discharge), menorrhagia (abnormally heavy bleeding at menstruation) and dysmenorrhea (Painful periods) after taking this medication. Inform your doctor and see a gynaecologist.

Question over 4 years ago

Does Flucole cause constipation?

Dr. Suhas Bhargav MBBS , General Physician

Occasionally, Flucole causes constipation when it is taken orally, while the interavenous administration of the medication does not cause constipation or other stomach related issues.



See all substitutes for Flucole


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Diflucan® (fluconazole)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 793-794

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