myUpchar प्लस+ के साथ पूरेे परिवार के हेल्थ खर्च पर भारी बचत

What is Angioedema?

Angioedema is a condition in which there is a swelling just below the skin in the dermis or the deeper skin tissues. It is generally an immune response to medication, food, pollen, environmental toxins or other allergens. It causes leakage of fluid through the blood vessels in the surrounding tissues causing swelling.

What are the main signs and symptoms of Angioedema?

Swelling on the lips, hands, feet, tongue, and around the eyes occur. Occasionally, an itchy or raised rash called urticaria or hives develops. Pain and mild itching, redness, warmth in the area are the other symptoms that are commonly seen. Oedema or swelling in the respiratory tract causes breathing issues. Oedema in the gastrointestinal tract causes, nausea, vomiting, diarrhoea, or pain.

What are its main causes?

The exact cause of angioedema is unknown. It is usually triggered by an allergic reaction to any allergen like a medication, insect bite, rubber latex, pet dander, or food.

Some medications generally tend to cause oedema. These include angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, and angiotensin receptor blockers.

Some people may inherit angioedema, which may be caused due to genetic modifications.

Few underlying medical conditions, such as infection or leukaemia, can also cause angioedema.

How is it diagnosed and treated?

Initially, doctors will physically examine you based on the symptoms. They may check the affected area and ask you about the medical history or exposure to any allergen. This will help determine the cause. Doctors may further perform some tests for allergies, such as the skin prick test or blood test. Blood testing specifically for C1 esterase inhibitor is performed. Low levels of this substance suggest that the problem is inherited. Abnormal results of tests, such as complement C2 or C4, can be due to an underlying condition.

Based on the cause of angioedema, doctors will prescribe medications. Sometimes, this condition does not require medication and resolves on its own. However, an aggressive form requires specific medical treatment. The main aim is to relieve swelling, itching, and pain.

Medications generally used are anti-itching drugs, anti-inflammatory drugs, drugs that suppress the immune system, drugs that reduce pain and swelling.

If angioedema is caused by an allergic reaction, avoiding the trigger may suffice. Anti-histaminic and steroidal medicines can be used in such conditions.

If angioedema is due to the use of some medications, then talk to your doctor about stopping your medicine and replacing it with a drug that is well tolerated.

Hereditary angioedema cannot be treated, but the symptoms can be treated using medicines that increase the level of C1 esterase inhibitor.

  1. Medicines for Angioedema

Medicines for Angioedema

Medicines listed below are available for Angioedema. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
PractinPractin Syrup87
Low DexLow Dex Eye/Ear Drops8
DexacortDexacort Eye Drop13
Dexacort (Klar Sheen)Dexacort (Klar Sheen) 0.1% Eye Drop14
4 Quin Dx4 Quin Dx Eye Drop13
SolodexSolodex 0.1% Eye/Ear Drops4
Apdrops DmApdrops Dm 0.5% W/V/1% W/V Eye Drop103
Hungree SyrupHungree Syrup58
Lupidexa CLupidexa C Eye Drop7
Dexcin MDexcin M Eye Drop59
Ocugate DxOcugate Dx Eye Drop8
Mfc DMfc D Eye Drop84
Mflotas DxMflotas Dx 0.5%W/V/0.1%W/V Eye Drop78
Mo 4 DxMo 4 Dx Eye Drop64
Moxifax DxMoxifax Dx Eye Drop52
Moxitak DmMoxitak Dm Eye Drops16
MyticomMyticom Eye Drop72
Occumox DmOccumox Dm 0.5%/0.1% Eye Drop0
Mflotas DMflotas D Eye Drop0
Mflotas TMflotas T Injection14
MilflodexMilflodex Eye Drop108
Milflox DmMilflox Dm Eye Drop18

Do you or anyone in your family have this disease? Please do a survey and help others

References

  1. National Health Service [Internet]. UK; Treatment - Angioedema
  2. MSDmannual consumer version [internet].Angioedema. Merck Sharp & Dohme Corp. Merck & Co., Inc., Kenilworth, NJ, USA
  3. Australasian Society of Clinical Immunology and Allergy. Angioedema. Australia; [internet]
  4. American Academy of Family Physicians. Urticaria and Angioedema: A Practical Approach. Am Fam Physician. 2004 Mar 1;69(5):1123-1129.
  5. Allen P Kaplan. Angioedema. World Allergy Organ J. 2008 Jun; 1(6): 103–113. PMID: 23282406
और पढ़ें ...