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Glibenclamide (Glyburide) + Metformin + Pioglitazone

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Glibenclamide (Glyburide) + Metformin + Pioglitazone Information

Glibenclamide (Glyburide) + Metformin + Pioglitazone Benefits & Uses

Glibenclamide (Glyburide) + Metformin + Pioglitazone is used to treat the following -

  1. टाइप 2 मधुमेह Primary
  2. Diabetes

Glibenclamide (Glyburide) + Metformin + Pioglitazone Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

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Ingredients of Glibenclamide (Glyburide) + Metformin + Pioglitazone

Glibenclamide (Glyburide)
Metformin
Pioglitazone

Glibenclamide (Glyburide) + Metformin + Pioglitazone Side Effects

Based on research, the following side effects have been observed when Glibenclamide (Glyburide) + Metformin + Pioglitazone is used -

  1. Hypoglycemia (Low blood sugar level)
  2. Nausea or vomiting
  3. Headache दुर्लभ
  4. Dizziness दुर्लभ
  5. Indigestion Mild
  6. Increased appetite
  7. Weight gain
  8. Constipation Moderate
  9. Heartburn Mild
  10. Dyspepsia
  11. Maculopapular rash
  12. Urticaria
  13. Muscle Ache Mild
  14. Flushing
  15. Erythema
  16. Jaundice Moderate
  17. Hepatitis
  18. Increased Liver Enzymes
  19. Altered taste
  20. Diarrhoea
  21. Abdominal Pain Mild
  22. Loss of appetite
  23. Stomach Upset
  24. Difficulty urinating
  25. Anxiety दुर्लभ
  26. Blurred vision
  27. Coma
  28. Pale Red Skin
  29. Flatulence Mild
  30. Palpitations (fluttering in chest)
  31. Chest Pain Moderate
  32. Numbness or tingling
  33. Broken bones (multiple fractures)
  34. Fatigue
  35. Irregular heartbeat
  36. Bloody Urine

Glibenclamide (Glyburide) + Metformin + Pioglitazone Related Warnings

Is the use of Glibenclamide (Glyburide) + Metformin + Pioglitazone safe for pregnant women?

Glibenclamide (Glyburide) + Metformin + Pioglitazone may have some side effects during pregnancy. Pregnant women should discontinue the use of Glibenclamide (Glyburide) + Metformin + Pioglitazone, and talk to their doctor, if they notice any discomfort.

Is the use of Glibenclamide (Glyburide) + Metformin + Pioglitazone safe during breastfeeding?

If you are breastfeeding, you may experience some harmful effects of Glibenclamide (Glyburide) + Metformin + Pioglitazone. In case you experience any of these, discontinue its use until you consult your doctor.

What is the effect of Glibenclamide (Glyburide) + Metformin + Pioglitazone on the Kidneys?

Glibenclamide (Glyburide) + Metformin + Pioglitazone rarely harms the kidneys.

What is the effect of Glibenclamide (Glyburide) + Metformin + Pioglitazone on the Liver?

You may experience side effects on your liver after taking Glibenclamide (Glyburide) + Metformin + Pioglitazone. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

What is the effect of Glibenclamide (Glyburide) + Metformin + Pioglitazone on the Heart?

There may be an adverse effect on the heart after taking Glibenclamide (Glyburide) + Metformin + Pioglitazone. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.

Severe Interaction of Glibenclamide (Glyburide) + Metformin + Pioglitazone with Other Drugs

Glibenclamide (Glyburide) + Metformin + Pioglitazone should not be taken with following medicines due to severe side effects it may cause to patients -

Glibenclamide (Glyburide) + Metformin + Pioglitazone Contraindications

If you are suffering from any of the following diseases, you should not take Glibenclamide (Glyburide) + Metformin + Pioglitazone unless your doctor advises you to do so -

  1. Allergy
  2. Liver Disease
  3. Kidney Disease
  4. Porphyria
  5. Trauma
  6. Heart Disease
  7. Congestive Heart Failure (CHF)
  8. Anemia
  9. Shock
  10. Heart Failure
  11. Liver Disease
  12. Heart Disease
  13. Hypoglycemia (Low Blood Sugar)
  14. Drug Allergy
  15. Kidney Disease
  16. Congestive Heart Failure (CHF)
  17. Liver Disease
  18. Anemia
  19. Bladder Cancer
  20. Diabetes Type 1
  21. Diabetic Ketoacidosis
  22. Allergy

Frequently asked Questions about Glibenclamide (Glyburide) + Metformin + Pioglitazone

Is this Glibenclamide (Glyburide) + Metformin + Pioglitazone habit forming or addictive?

Glibenclamide (Glyburide) + Metformin + Pioglitazone is not addictive in nature.

Is it safe to drive or operate heavy machinery when consuming?

Yes, you can comfortably use machinery or drive after taking Glibenclamide (Glyburide) + Metformin + Pioglitazone since it will not make you feel sleepy.

Is it safe?

Yes, but consume Glibenclamide (Glyburide) + Metformin + Pioglitazone only on doctor's advice.

Is it able to treat mental disorders?

Glibenclamide (Glyburide) + Metformin + Pioglitazone is unable to treat or cure mental disorders.

Glibenclamide (Glyburide) + Metformin + Pioglitazone Interactions with Food and Alcohol

Interaction between Food and Glibenclamide (Glyburide) + Metformin + Pioglitazone

Due to the absence of research, it is difficult to say how Glibenclamide (Glyburide) + Metformin + Pioglitazone and food will interact.

Interaction between Alcohol and Glibenclamide (Glyburide) + Metformin + Pioglitazone

Side effects of drinking alcohol and taking Glibenclamide (Glyburide) + Metformin + Pioglitazone at the same time are rare and minor. However, if you face any side effects, talk to your doctor immediately.

This medicine data has been created by -
Md Saadullah
M.Pharma, Pharmacy
3 Years of Experience
View Doctor Profile
Dr. Vikas Chauhan
B.Pharma, Pharmacy
2 Years of Experience
View Doctor Profile

References

  1. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glynase® PresTab® (micronized glyburide)
  2. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 272
  3. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
  4. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
  5. April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826
  6. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Actos (pioglitazone hydrochloride)
  7. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 276-277
  8. April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1032-1033
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