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Markzole, a prescription drug, is manufactured in various forms such as Tablet. Primarily, it is used for the treatment of Fungal Infections, Candidal Infection, Urinary Tract Infection. Secondary and off-label uses of Markzole have also been mentioned below.
The optimal dosage of Markzole is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.
Apart from the aforementioned side effects, Markzole can also lead to other problems, which have been listed below. Normally, these side effects of Markzole are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.
In addition, Markzole's effect is Severe during pregnancy and Safe for lactating mothers. Further, the section on Markzole related warnings talks about Markzole's effects on the liver, heart and kidney.
Markzole is not recommended if you suffer from certain medical conditions as it can have adverse effects. Liver Disease are examples of such conditions. Other conditions have been mentioned below in the Markzole contraindications section.
Drug interactions for Markzole have been reported in the medical literature. See below for a complete list.
You should also be aware that Markzole is not safe while driving, and is not addiction.
Markzole is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult(Female) |
|
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Based on research, the following side effects have been observed when Markzole is used -
Severe
Moderate
Mild
Is the use of Markzole safe for pregnant women?
Markzole has many dangerous side effects in pregnant women. If you are pregnant, do not consume Markzole without medical advice.
Is the use of Markzole safe during breastfeeding?
Markzole does not show any side effects in breastfeeding women.
What is the effect of Markzole on the Kidneys?
Markzole may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.
What is the effect of Markzole on the Liver?
Markzole has very mild side effects on the liver.
What is the effect of Markzole on the Heart?
Very few cases of side effects of Markzole on the heart have been reported.
Markzole should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Markzole unless your doctor advises you to do so -
Is this Markzole habit forming or addictive?
Markzole is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
No, you should do not do anything that requires concentration and attention as the Markzole can make you feel drowsy.
Is it safe?
Markzole should be used only after doctor's advice.
Is it able to treat mental disorders?
No, Markzole cannot treat any kind of mental disorder.
Interaction between Food and Markzole
Taking Markzole with food is safe.
Interaction between Alcohol and Markzole
It is difficult to say anything about the effect of Markzole and alcohol. No research has been done on this yet.
Discontinuation of Markzole on your own can cause unwanted side effects such as a headache, dizziness, stomach upset, and diarrhea. You are recommended to always consult a doctor before discontinuing this medicine.
Yes, Markzole is widely used in the treatment of jock itch (tinea cruris). It is a prescription medicine so please consult your doctor before using this medication for tinea cruris.
Occasionally, Markzole causes constipation when it is taken orally, while the interavenous administration of the medication does not cause constipation or other stomach related issues.
Rarely, Markzole can cause irregular periods. However, if you're experiencing conditions such as leucorrhoea (whitish or yellowish vaginal discharge), menorrhagia (abnormally heavy bleeding at menstruation) and dysmenorrhea (Painful periods) after taking this medication. Inform your doctor and see a gynaecologist.
Markzole inhibit the fungal cytochrome P450 enzyme lanosterol 14- demethylase and thus block ergosterol synthesis leading to membrane abnormalities in the fungus. It kills the fungus by destroying its cell membrane.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Diflucan® (fluconazole)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 793-794