Paclitrust

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Paclitrust Information

Paclitrust is a commercial drug that is prescribed in the form of Injection. Breast Cancer are some of its major therapeutic uses. Paclitrust also has some secondary and off-label uses. These are listed below.

The right dosage of Paclitrust depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Paclitrust as well, which are listed below. Such side effects of Paclitrust normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Paclitrust is Severe for pregnant women and Severe for women who are breastfeeding. Further, the section on Paclitrust related warnings talks about Paclitrust's effects on the liver, heart and kidney.

Paclitrust can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Paclitrust in conditions like Liver Disease, Herpes, Heart Disease. Some other conditions that can be affected by Paclitrust are listed in the contraindications section below.

Drug interactions for Paclitrust have been reported in the medical literature. Refer to the list below for further details.

In addition to the above precautions for Paclitrust, it is important to know that it is not safe while driving, and is not habit-forming.


Paclitrust Benefits & Uses

Paclitrust is used to treat the following -

Other Benefits

Paclitrust Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult(Female)
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 300 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Given in every 3 weeks followed by cisplatin
Adult
  • Disease: Non-Small Cell Lung Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 225 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Given in every 3 weeks followed by cisplatin
Geriatric
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 300 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Given in every 3 weeks followed by cisplatin

Paclitrust Related Warnings

  • Is the use of Paclitrust safe for pregnant women?


    Pregnant women may get severe side effects after taking Paclitrust. If you are pregnant, do not take Paclitrust without a doctor's advice.

    Severe
  • Is the use of Paclitrust safe during breastfeeding?


    Taking Paclitrust may lead to serious side effects if you are breastfeeding. Paclitrust should not be taken by breastfeeding women unless prescribed by the doctor.

    Severe
  • What is the effect of Paclitrust on the Kidneys?


    Paclitrust does not damage the kidneys.

    Safe
  • What is the effect of Paclitrust on the Liver?


    You may experience side effects on your liver after taking Paclitrust. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Paclitrust on the Heart?


    Paclitrust has very mild side effects on the heart.

    Mild

Severe Interaction of Paclitrust with Other Drugs

Paclitrust should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Emtricitabine,Tenofovir,Efavirenz
    Ketoconazole

    Paclitrust Contraindications

    If you are suffering from any of the following diseases, you should not take Paclitrust unless your doctor advises you to do so -


    Frequently asked Questions about Paclitrust

    • Is this Paclitrust habit forming or addictive?


      Forming a habit of Paclitrust has not been reported.

      No
    • Is it safe to drive or operate heavy machinery when consuming?


      You may feel sleepy or tired after taking Paclitrust. So it is best to avoid driving.

      Dangerous
    • Is it safe?


      Paclitrust should be used only after doctor's advice.

      Safe, but take only on Doctor's advise
    • Is it able to treat mental disorders?


      No, Paclitrust is not used to treat mental disorders.

      No

    Paclitrust Interactions with Food and Alcohol

    • Interaction between Food and Paclitrust


      It is safe to take Paclitrust with food.

      Safe
    • Interaction between Alcohol and Paclitrust


      Consumption of alcohol and Paclitrust together may have severe effects on your health.

      Severe

    See all substitutes for Paclitrust


    This medicine data has been created by -

    Vikas Chauhan
    B.Pharma, Pharmacy
    5 Years of Experience

    References

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 967-969

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 865-866

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Taxol® (paclitaxel)

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user;Abraxane® (paclitaxel protein-bound particles)


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