Supral Plus

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  • Contains / Salt: Olanzapine (5 mg) + Fluoxetine (20 mg)
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Supral Plus Information

Supral Plus is a commercial drug that is prescribed in the form of Tablet. It is typically used for the treatment of Schizophrenia. Secondary and off-label uses of Supral Plus have also been mentioned below.

The correct dosage of Supral Plus depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

Some other side effects of Supral Plus have been listed ahead. Such side effects of Supral Plus normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

Supral Plus's effect during pregnancy is Moderate and Severe while nursing. Warnings related to Supral Plus's effects on the liver, heart and kidney, if any, have been listed below.

Supral Plus can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Supral Plus in conditions like Tardive Dyskinesia, Depression. Other contraindications of Supral Plus have been discussed in the sections ahead.

Additionally, Supral Plus may also adversely react with other medicines. A complete list of these interactions is given below.

In addition to these precautions, you may also note that Supral Plus is not safe while driving, and is is not addictive in nature.



Supral Plus Benefits & Uses

Supral Plus is used to treat the following -

Main Benefits

Other Benefits

Supral Plus Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 10 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 5 - 20 mg/day
Geriatric
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 5 - 10 mg/day
13 - 18 years (Adolescent)
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 5 - 10 mg/day

Supral Plus Related Warnings

  • Is the use of Supral Plus safe for pregnant women?


    Pregnant women may experience moderate side effects from Supral Plus. It is best to stop taking Supral Plus immediately and inform your doctor if you notice any discomfort.

    Moderate
  • Is the use of Supral Plus safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Supral Plus. It should only be taken after medical advice.

    Severe
  • What is the effect of Supral Plus on the Kidneys?


    There are no side effects of Supral Plus on the kidneys.

    Safe
  • What is the effect of Supral Plus on the Liver?


    Supral Plus is rarely harmful for the liver.

    Mild
  • What is the effect of Supral Plus on the Heart?


    Side effects of Supral Plus rarely affect the heart.

    Mild


Severe Interaction of Supral Plus with Other Drugs

Supral Plus should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Supral Plus Contraindications

If you are suffering from any of the following diseases, you should not take Supral Plus unless your doctor advises you to do so -



Frequently asked Questions about Supral Plus

  • Is this Supral Plus habit forming or addictive?


    Supral Plus is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Supral Plus can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Supral Plus only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, Supral Plus is useful in treating mental disorders.

    Yes

Supral Plus Interactions with Food and Alcohol

  • Interaction between Food and Supral Plus


    Supral Plus may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.

    Mild
  • Interaction between Alcohol and Supral Plus


    Consumption of alcohol and Supral Plus together may have severe effects on your health.

    Severe


Frequently asked Questions about Supral Plus

Question about 5 years ago

How long can I safely take Supral Plus?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Take Supral Plus as directed by your doctor. Do not take this medicine longer than prescribed by your doctor to avoid unpleasant side effects.

Question about 5 years ago

Can I discontinue Supral Plus on my own without doctors advice?

Dr. Prakash kumar MBBS , General Physician

No, Supral Plus should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.

Question almost 5 years ago

Does Supral Plus cause drowsiness?

Dr. Ramraj MBBS , Other

Yes, Supral Plus may cause drowsiness or sedation. It is a common side effect of this drug. It occurs because this drug affects the levels of chemical messengers in your brain. You are advised not to drive any vehicle or operate heavy machinery after taking this drug to avoid accidents

Question over 4 years ago

Can Supral Plus help with OCD (obsessive-compulsive disorder)?

Dr. Madhur Anand MBBS, MS , General Surgery

Yes, Supral Plus might help with OCD (obsessive-compulsive disorder) in those patients who are unresponsive to the conventional treatment. Scientific data suggests that it might improve the mood symptoms in the treatment of unresponsive OCD patients.

Question almost 5 years ago

Can Supral Plus cause mania?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Yes, Supral Plus might cause mania. It is a rare side effect of this drug and the exact cause behind mania is unknown. If you are experiencing any unusual changes in personality, behavior (aggression), and thoughts. Then you are advised to discuss it with your doctor without any further delay.



See all substitutes for Supral Plus


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 932-934

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 442

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyprexa (olanzapine)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyprexa Intramuscular (olanzapine)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyprexa Relprevv (olanzapine)

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