Duloxetine



  • Manufactured by:
  • Contains / Salt: Duloxetine


Duloxetine Information

Duloxetine is a prescription medicine. It is typically used for the treatment of Depression, Anxiety, Diabetic Neuropathy. Secondary and off-label uses of Duloxetine have also been mentioned below.

Medical history of the patient along with age and gender determines the dosage of Duloxetine. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

Apart from the aforementioned side effects, Duloxetine can also lead to other problems, which have been listed below. Such side effects of Duloxetine normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Duloxetine's effect during pregnancy is Moderate and Severe while nursing. It is important to know if Duloxetine has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Duloxetine related warnings section.

Individuals suffering from medical conditions like Kidney Disease, Liver Disease must refrain from the use of Duloxetine since this can cause severe adverse effects. Some other conditions that can be affected by Duloxetine are listed in the contraindications section below.

Besides this, Duloxetine may also have severe interaction with some medicines. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Duloxetine is considered not safe while driving, and is not addictive.



Duloxetine Benefits & Uses

Duloxetine is used to treat the following -

Other Benefits

Duloxetine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 30 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
Geriatric
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 30 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
13 - 18 years (Adolescent)
  • Disease: Anxiety
  • Before or After Meal: After Meal
  • Single Maximum Dose: 60 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice

Duloxetine Related Warnings

  • Is the use of Duloxetine safe for pregnant women?


    Duloxetine can have harmful effects in pregnant women. If you experience any discomfort after using Duloxetine, then discontinue the use and take your doctor's advice.

    Moderate
  • Is the use of Duloxetine safe during breastfeeding?


    Duloxetine should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Duloxetine on the Kidneys?


    Duloxetine has very mild side effects on the kidneys.

    Mild
  • What is the effect of Duloxetine on the Liver?


    Duloxetine is rarely harmful for the liver.

    Mild
  • What is the effect of Duloxetine on the Heart?


    Duloxetine may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Duloxetine with Other Drugs

Duloxetine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Duloxetine Contraindications

If you are suffering from any of the following diseases, you should not take Duloxetine unless your doctor advises you to do so -



Frequently asked Questions about Duloxetine

  • Is this Duloxetine habit forming or addictive?


    No, there is no any evidence that Duloxetine is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Duloxetine, you should not drive or work on any heavy machine, as Duloxetine can make you drowsy.

    Dangerous
  • Is it safe?


    Yes, Duloxetine is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, this Duloxetine works for mental disorders.

    Yes

Duloxetine Interactions with Food and Alcohol

  • Interaction between Food and Duloxetine


    Eating certain foods may increase the time it takes Duloxetine to have an effect. You should consult your doctor about it.

    Mild
  • Interaction between Alcohol and Duloxetine


    Consuming Duloxetine with alcohol can have many serious effects on your body.

    Severe


See all substitutes for Duloxetine


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 474-475

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 462

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cymbalta (duloxetine hydrochloride)

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