Promethazine

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  • Contains / Salt: Promethazine
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Promethazine Tablet Information

Promethazine Tablet is a prescription medicine. It is primarily used for the treatment of Nausea and Vomiting. The alternative uses of Promethazine Tablet have also been explained below.

The right dosage of Promethazine Tablet depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

Besides the aforementioned side effects, there are other adverse effects of Promethazine Tablet as well, which are listed below. Usually, these side effects of Promethazine Tablet go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Promethazine Tablet is Moderate for pregnant women and Moderate for women who are breastfeeding. It is important to know if Promethazine Tablet has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Promethazine Tablet related warnings section.

Promethazine Tablet can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Promethazine Tablet in conditions like Heart Disease, Asthma. Other conditions have been mentioned below in the Promethazine Tablet contraindications section.

Drug interactions for Promethazine Tablet have been reported in the medical literature. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Promethazine Tablet is considered not safe while driving, and is not addictive.



Promethazine Tablet Benefits & Uses

Promethazine Tablet is used to treat the following -

Other Benefits

Promethazine Tablet Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage


Promethazine Tablet Side Effects

Based on research, the following side effects have been observed when Promethazine Tablet is used -

Severe

  • Drowsiness
  • Headache
  • Seizures (uncontrollable jerking of limbs)
  • Tremor

Moderate

Mild

  • Injection Site Allergic Reaction

Promethazine Tablet Related Warnings

  • Is the use of Promethazine Tablet safe for pregnant women?


    Promethazine can have harmful effects in pregnant women. If you experience any discomfort after using Promethazine, then discontinue the use and take your doctor's advice.

    Moderate
  • Is the use of Promethazine Tablet safe during breastfeeding?


    If you are breastfeeding, you may experience some harmful effects of Promethazine. In case you experience any of these, discontinue its use until you consult your doctor.

    Moderate
  • What is the effect of Promethazine Tablet on the Kidneys?


    Using Promethazine does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Promethazine Tablet on the Liver?


    Side effects of Promethazine rarely affect the liver.

    Mild
  • What is the effect of Promethazine Tablet on the Heart?


    Promethazine has very mild side effects on the heart.

    Mild


Severe Interaction of Promethazine Tablet with Other Drugs

Promethazine Tablet should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Promethazine Tablet Contraindications

If you are suffering from any of the following diseases, you should not take Promethazine Tablet unless your doctor advises you to do so -



Frequently asked Questions about Promethazine Tablet

  • Is this Promethazine Tablet habit forming or addictive?


    Forming a habit of Promethazine Tablet has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Promethazine Tablet you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, but take Promethazine Tablet only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, this Promethazine Tablet works for mental disorders.

    Yes

Promethazine Tablet Interactions with Food and Alcohol

  • Interaction between Food and Promethazine Tablet


    It is safe to take Promethazine Tablet with food.

    Safe
  • Interaction between Alcohol and Promethazine Tablet


    Consult your doctor before consuming alcohol while taking Promethazine Tablet as it can have severe side effects.

    Severe


Frequently asked Questions about Promethazine Tablet

Question over 4 years ago

Can I take Promethazine with amitriptyline?

Dr. MBBS , Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

No, it is recommended that you do not take Promethazine with amitriptyline which is an antidepressant with anticholinergic effects. Since Promethazine also has anticholinergic effects, both the drugs produce additive effects such as dry mouth, constipation, blurred vision, etc. 

Question about 5 years ago

How to take Promethazine?

Dr. Chinmaya Bal MBBS , General Physician

Promethazine is available in the form of injectable, tablets and syrups to be taken orally, as a suppository to be taken rectally. When taken for treating allergies, it is taken 1 to 4 times a day usually before meals or at bedtime. When used for treating cold, it is taken every 4 to 6 hours. When used for treating motion sickness, it is taken 30 to 60 minutes before travel and again after 8 to 10 hours if required. Promethazine might also be taken at bedtime before surgery to feel relaxed and sleep properly. The suppositories are meant for rectal use. Do not use them in any other body cavity. If using Promethazine liquid, avoid using a household spoon and use the measuring cup that is dispensed with the syrup. The Promethazine should be taken exactly as prescribed by your doctor.

Question almost 5 years ago

Does Promethazine cause dry mouth?

Dr. MBBS , Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

Yes, antipsychotics like Promethazine exert anticholinergic effects and as a result, dry mouth is one of the adverse reactions. Some of the additional anticholinergic effects are constipation, urinary retention, and blurred vision. If any of these effects present, it is important that you talk to your doctor immediately.

Question almost 5 years ago

Does Promethazine cause weight gain?

Dr. Gaurav MBBS , General Physician

Most antipsychotics cause weight gain and Promethazine is also one of the drugs that cause the same. Promethazine induces sleep and causes lethargy in patients due to which the physical activity gets reduced, leading to weight gain. Since weight loss is difficult for most people, emphasis should be paid on preventing weight gain using lifestyle modifications comprising a change of diet and the addition of physical activity in routine. 

Question over 4 years ago

Can I take Promethazine with Zantac?

Dr. Bharat MBBS , General Physician

Yes, Promethazine can be safely taken with Zantac, which is used for managing acidity and prevent ulcers in stomach and intestine.



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Phenergan (promethazine HCI)



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