Combace

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5 ml Drops in 1 Bottle Out of Stock
₹ 12
5 ML DROPS 1 Bottle ₹ 12
  • Out of Stock

  • Manufactured by:
  • Contains / Salt: Moxifloxacin (0.5 % w/v) + Prednisolone (1 % w/v)
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Combace Information

Combace is a prescription drug, available for use as Drops. Primarily, it is used for the treatment of Conjunctivitis. Other than this, Combace has some other therapeutic uses, which have been discussed ahead.

The right dosage of Combace depends on the age, gender, and medical history of the patient. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.

The side effects typically associated with Combace include Eye irritation, Eye itching, Eye Pain. Such side effects of Combace normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Combace is Unknown for pregnant women and Unknown for women who are breastfeeding. In addition, Combace's effects on the liver, heart and kidney are discussed below in the Combace related warnings section.

Combace is contraindicated in people with pre-existing medical conditions like Allergy as it can result in adverse effects.

Drug reaction of Combace with other medicines has been reported. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Combace is considered not safe while driving, and is not addictive.



Combace Benefits & Uses

Combace is used to treat the following -

Main Benefits

Other Benefits

Combace Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease: Conjunctivitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: 7 days
  • Special Instructions: Dosage strength: Moxifloxacin (0.5% w/v) + Prednisolone (1% w/v)
2 - 12 years (Child)
  • Disease: Conjunctivitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 1 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: 7 days
  • Special Instructions: Dosage strength: Moxifloxacin (0.5% w/v) + Prednisolone (1% w/v)
Adult
  • Disease: Conjunctivitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: 7 days
  • Special Instructions: Dosage strength: Moxifloxacin (0.5% w/v) + Prednisolone (1% w/v)
Geriatric
  • Disease: Conjunctivitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 drop
  • Dosage Route: Ophthalmic
  • Frequency: 4 daily
  • Course Duration: 7 days
  • Special Instructions: Dosage strength: Moxifloxacin (0.5% w/v) + Prednisolone (1% w/v)


Combace Side Effects

Based on research, the following side effects have been observed when Combace is used -

Common

  • Eye irritation
  • Eye itching
  • Eye Pain

Combace Related Warnings

  • Is the use of Combace safe for pregnant women?


    It is not known what effect Combace will have on pregnant women, because no research work has been carried out on this till date.

    Unknown
  • Is the use of Combace safe during breastfeeding?


    Information about safety of Combace for women who are breastfeeding is not available since scientific research on this is yet to be done.

    Unknown
  • What is the effect of Combace on the Kidneys?


    There are no side effects of Combace on the kidneys.

    Safe
  • What is the effect of Combace on the Liver?


    There are no any side effects of Combace on the liver.

    Safe
  • What is the effect of Combace on the Heart?


    Combace is completely safe for the heart.

    Safe


Severe Interaction of Combace with Other Drugs

Combace should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Combace Contraindications

If you are suffering from any of the following diseases, you should not take Combace unless your doctor advises you to do so -



Frequently asked Questions about Combace

  • Is this Combace habit forming or addictive?


    Combace does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Combace can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but consume Combace only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Combace in mental disorders is not effective.

    No

Combace Interactions with Food and Alcohol

  • Interaction between Food and Combace


    You can take Combace with food.

    Safe
  • Interaction between Alcohol and Combace


    No research has been done on this till date. Therefore, it is not known what the effect of taking Combace with alcohol will be.

    Unknown


Frequently asked Questions about Combace

Question almost 5 years ago

Does Combace cause diarrhoea?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, oral Combace may cause diarrhoea. It is a common side effect of this drug. To keep yourself well hydrated, drink plenty of fluids while you are taking this drug. If you are experiencing severe diarrhoea after taking this drug then discuss with your doctor immediately without any further delay. 

Question almost 4 years ago

Can I take Combace with aspirin?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, Combace can be taken with aspirin. No drug-drug interaction has been reported between them. It is safe to take Combace along with aspirin if it does not exceed recommended doses. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

Question over 4 years ago

Does Combace cover anaerobes?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, Combace covers anaerobes. It is effective against some of the anaerobic bacteria such as Bacteroides fragilis, Bacteroides thetaiotaomicron, Clostridium perfringens, and Peptostreptococcus species.

Question over 4 years ago

Can Combace be used for pink eye?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, eye drops of Combace can be used in a pink eye (conjunctivitis). It is given in the treatment of pink eye if it is caused by the bacteria. Since Combace is a prescription drug you are advised not to use Combace by yourself to avoid bacterial resistance and unpleasant side effects.

Question over 4 years ago

Does Combace cover pseudomonas?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Combace does not cover strains of Pseudomonas aeruginosa. It is generally found to be resistant to Combace. Hence other antibiotics which are active against Pseudomonas aeruginosa should be used.



See all substitutes for Combace


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 579-584

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 714

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Avelox (moxifloxacin hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Orapred ODT® (prednisolone sodium phosphate

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 872

Product Description [Internet]: OCCUMOX P. Sunways

Highlights Of Prescribing Information [Internet]: VIGAMOX® (moxifloxacin hydrochloride ophthalmic solution) 0.5% as base Sterile topical ophthalmic solution. USFDA

April Hazard Vallerand, Cynthia A. Sanoski. Davis’s Drug Guide For Nurses. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1402.

Product Description [Internet]: OMNIPRED™ (prednisolone acetate ophthalmic suspension). USFDA

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