Amikamac 250 Injection

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1 Injection in 1 Packet
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1 INJECTION 1 Packet ₹ 38
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Mikacin 250 mg Injection
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Amikamac 250 Injection Information

Amikamac 250 Injection is a commercial drug that is prescribed in the form of Injection. It is typically used for the treatment of Urinary Tract Infection. Amikamac 250 Injection also has some secondary and off-label uses. These are listed below.

The optimal dosage of Amikamac 250 Injection is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

While these are the most often observed Amikamac 250 Injection side effects, there are can be others also. These have been listed below. Such side effects of Amikamac 250 Injection normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

It is also important to note that Amikamac 250 Injection has a Severe effect for pregnant women and Unknown effect on lactating mothers. Further, the section on Amikamac 250 Injection related warnings talks about Amikamac 250 Injection's effects on the liver, heart and kidney.

Amikamac 250 Injection can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Amikamac 250 Injection in conditions like Dehydration, Parkinson's Disease, Hearing Loss. The section on Amikamac 250 Injection contraindications lists all such conditions.

Drug interactions for Amikamac 250 Injection have been reported in the medical literature. Refer to the list below for further details.

In addition to the above precautions for Amikamac 250 Injection, it is important to know that it is safe while driving, and is habit-forming.



Amikamac 250 Injection Benefits & Uses

Amikamac 250 Injection is used to treat the following -

Main Benefits

Other Benefits

Amikamac 250 Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Bacterial Infections
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Urinary Tract Infection (UTI)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor

Amikamac 250 Injection Related Warnings

  • Is the use of Amikamac 250 Injection safe for pregnant women?


    Pregnant women may get severe side effects after taking Amikamac. If you are pregnant, do not take Amikamac without a doctor's advice.

    Severe
  • Is the use of Amikamac 250 Injection safe during breastfeeding?


    No research work has been carried out till date on effect of Amikamac on breastfeeding women. So it is not known whether taking Amikamac will cause side effects or not.

    Unknown
  • What is the effect of Amikamac 250 Injection on the Kidneys?


    Effects of Amikamac on kidney can be severe. It is not safe to use it without doctor's advice.

    Severe
  • What is the effect of Amikamac 250 Injection on the Liver?


    Amikamac is rarely harmful for the liver.

    Mild
  • What is the effect of Amikamac 250 Injection on the Heart?


    Amikamac has very mild side effects on the heart.

    Mild


Amikamac 250 Injection Contraindications

If you are suffering from any of the following diseases, you should not take Amikamac 250 Injection unless your doctor advises you to do so -



Frequently asked Questions about Amikamac 250 Injection

  • Is this Amikamac 250 Injection habit forming or addictive?


    Amikamac 250 Injection does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Amikamac 250 Injection since it does not cause drowsiness.

    Safe
  • Is it safe?


    Yes, but consume Amikamac 250 Injection only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Amikamac 250 Injection for mental disorders.

    No

Amikamac 250 Injection Interactions with Food and Alcohol

  • Interaction between Food and Amikamac 250 Injection


    Taking Amikamac 250 Injection with food does not harm your health.

    Safe
  • Interaction between Alcohol and Amikamac 250 Injection


    It is difficult to say anything about the effect of Amikamac 250 Injection and alcohol. No research has been done on this yet.

    Unknown


Frequently asked Questions about Amikamac 250 Injection

Question about 5 years ago

Can I take Amikamac with penicillin?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Amikamac cannot be taken with penicillin. Because penicillin inactivates the Amikamac by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Amikamac should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function. 

Question over 5 years ago

How to take Amikamac?

Dr. Abhijit MBBS , General Physician

Do not self-administer Amikamac. It comes in the form of injection and given preferably 2 - 3 times in a day (Intravenously). Discontinuing the medicine in between may promote resistant bacteria which result in a relapse of the infection. You are recommended to complete the 7 - 10 days course even after getting symptomatic relief. In case you feel any discomfort such as hearing loss and nephrotoxicity while taking Amikamac please inform your doctor immediately. 

Question over 5 years ago

What is Amikamac?

Amikamac is a brand name for amikacin. It is a prescription drug which belongs to the class of medication known as an aminoglycoside antibiotic. It is a broad spectrum antibiotic which is used for the treatment of bacterial infection such as bone, joint, skin, intra-abdominal, pneumonia, and respiratory tract infection. It is used for short-term treatment (7 - 10 days) of bacterial infection in different part of the body. It is also used for the treatment of neonatal sepsis when sensitivity testing indicates that other aminoglycosides cannot be used.

Question about 5 years ago

Can I take Amikamac without consulting a doctor?

Dr. Abhijit MBBS , General Physician

Amikamac is a prescription drug, hence do not take Amikamac without consulting doctor. It can be harmful to patients to take this medicine without a doctor's advice.

Question over 5 years ago

Can I discontinue Amikamac on my own without doctors advice?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

Discontinuing Amikamac on your own can increase the chances of bacterial resistance and infection relapse. It is recommended that you always consult your doctor if you have decided to discontinue this medicine.



See all substitutes for Amikamac



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137

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