Duloxetine is a prescription medicine. It is typically used for the treatment of Depression, Anxiety, Diabetic Neuropathy. Secondary and off-label uses of Duloxetine have also been mentioned below.
Medical history of the patient along with age and gender determines the dosage of Duloxetine. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.
Apart from the aforementioned side effects, Duloxetine can also lead to other problems, which have been listed below. Such side effects of Duloxetine normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.
Duloxetine's effect during pregnancy is Moderate and Severe while nursing. It is important to know if Duloxetine has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Duloxetine related warnings section.
Individuals suffering from medical conditions like Kidney Disease, Liver Disease must refrain from the use of Duloxetine since this can cause severe adverse effects. Some other conditions that can be affected by Duloxetine are listed in the contraindications section below.
Besides this, Duloxetine may also have severe interaction with some medicines. A complete list of these interactions is given below.
Along with the above-mentioned precautions, remember that taking Duloxetine is considered not safe while driving, and is not addictive.
Duloxetine is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
| 13 - 18 years (Adolescent) |
|
Based on research, the following side effects have been observed when Duloxetine is used -
Moderate
Mild
Is the use of Duloxetine safe for pregnant women?
Duloxetine can have harmful effects in pregnant women. If you experience any discomfort after using Duloxetine, then discontinue the use and take your doctor's advice.
Is the use of Duloxetine safe during breastfeeding?
Duloxetine should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.
What is the effect of Duloxetine on the Kidneys?
Duloxetine has very mild side effects on the kidneys.
What is the effect of Duloxetine on the Liver?
Duloxetine is rarely harmful for the liver.
What is the effect of Duloxetine on the Heart?
Duloxetine may have mild side effects on the heart. Most people will never see any effect on the heart.
Duloxetine should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Duloxetine unless your doctor advises you to do so -
Is this Duloxetine habit forming or addictive?
No, there is no any evidence that Duloxetine is addictive.
Is it safe to drive or operate heavy machinery when consuming?
After taking Duloxetine, you should not drive or work on any heavy machine, as Duloxetine can make you drowsy.
Is it safe?
Yes, Duloxetine is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
Yes, this Duloxetine works for mental disorders.
Interaction between Food and Duloxetine
Eating certain foods may increase the time it takes Duloxetine to have an effect. You should consult your doctor about it.
Interaction between Alcohol and Duloxetine
Consuming Duloxetine with alcohol can have many serious effects on your body.
This medicine data has been created by -
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 474-475
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 462
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cymbalta (duloxetine hydrochloride)
